Perillic acid

Perillic acid is a lipid of Prenol Lipids (PR) class. The involved functions are known as Membrane Potential, Mitochondrial, Neuroprotection, inhibitors, Protein Geranylgeranylation and mitochondrial depolarization. Perillic acid often locates in Membrane and Extracellular. The associated genes with Perillic acid are RAB3A gene and neutrophil cytosol factor 67K.

Cross Reference

Introduction

To understand associated biological information of Perillic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Perillic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Perillic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Perillic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Perillic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Perillic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Perillic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Perillic acid

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Authors Title Published Journal PubMed Link
Samaila D et al. Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. 2004 Sep-Oct Anticancer Res. pmid:15517920
Bailey HH et al. A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days. 2004 Cancer Chemother. Pharmacol. pmid:15205914
Duetz WA et al. Biotransformation of limonene by bacteria, fungi, yeasts, and plants. 2003 Appl. Microbiol. Biotechnol. pmid:12743755
Beaupre DM et al. Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells. 2003 Leuk. Lymphoma pmid:14959858
Holstein SA and Hohl RJ Monoterpene regulation of Ras and Ras-related protein expression. 2003 J. Lipid Res. pmid:12671036
Azzoli CG et al. A phase I trial of perillyl alcohol in patients with advanced solid tumors. 2003 Cancer Chemother. Pharmacol. pmid:12695855
Choy WY et al. Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery. 2002 Eur. J. Pharmacol. pmid:11755166
Chow HH et al. Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content. 2002 Cancer Epidemiol. Biomarkers Prev. pmid:12433729
Bardon S et al. Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. 2002 Cancer Lett. pmid:12175534
Ferri N et al. Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation. 2001 Biochem. Pharmacol. pmid:11755117