Thujone

Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.

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Introduction

To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thujone?

Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thujone

MeSH term MeSH ID Detail
Seizures D012640 87 associated lipids
Insulin Resistance D007333 99 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Thujone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thujone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thujone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thujone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Thujone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thujone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thujone

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Authors Title Published Journal PubMed Link
Nikolić B et al. Modulation of genotoxicity and DNA repair by plant monoterpenes camphor, eucalyptol and thujone in Escherichia coli and mammalian cells. 2011 Food Chem. Toxicol. pmid:21620923
Hudson J et al. The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings. 2011 Int J Environ Res Public Health pmid:22408584
Walch SG et al. Antioxidant Capacity and Polyphenolic Composition as Quality Indicators for Aqueous Infusions of Salvia officinalis L. (sage tea). 2011 Front Pharmacol pmid:22194722
Font X et al. Detection, composition and treatment of volatile organic compounds from waste treatment plants. 2011 Sensors (Basel) pmid:22163835
Tenore GC et al. Antimicrobial and antioxidant properties of the essential oil of Salvia lanigera from Cyprus. 2011 Food Chem. Toxicol. pmid:20977923
Lachenmeier DW and Walch SG The choice of thujone as drug for diabetes. 2011 Nat. Prod. Res. pmid:21988529
Alkhateeb H et al. Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation. 2011 Appl Physiol Nutr Metab pmid:21574785
Toxicology and carcinogenesis studies of alpha,beta-thujone (CAS No. 76231-76-0) in F344/N rats and B6C3F1 mice (gavage studies). 2011 Natl Toxicol Program Tech Rep Ser pmid:22127327
Baddar NW et al. Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. 2011 Nat. Prod. Res. pmid:21740283
Singh O et al. Chamomile (Matricaria chamomilla L.): An overview. 2011 Pharmacogn Rev pmid:22096322