Politzer WM |
Long-term clinical remission of a patient with chronic lymphocytic leukemia using alternative treatment option: cottonseed oil (gossypol). |
2008 |
Phytomedicine |
pmid:18573644
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Shaaban WF et al. |
Reproductive toxicologic effects of gossypol on male rabbits: biochemical, enzymatic, and electrolytic properties of seminal plasma. |
2008 |
Fertil. Steril. |
pmid:17953964
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Li ZM et al. |
Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin's lymphoma cells. |
2008 |
Cancer Biol. Ther. |
pmid:17938578
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Jia L et al. |
Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate. |
2008 |
Cancer Chemother. Pharmacol. |
pmid:17356822
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Przybylski P et al. |
EI MS and ESI MS studies of the bisesquiterpene from cotton seeds: Gossypol and its Aza-derivatives. |
2008 |
J Mass Spectrom |
pmid:18200654
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Kitada S et al. |
Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048). |
2008 |
Blood |
pmid:18202226
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Tang G et al. |
Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins. |
2008 |
J. Med. Chem. |
pmid:18237106
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Kline MP et al. |
R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. |
2008 |
Exp. Hematol. |
pmid:18346839
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Gao F et al. |
Interactive effects of elevated CO2 and cotton cultivar on tri-trophic interaction of Gossypium hirsutum, Aphis gossyppii, and Propylaea japonica. |
2008 |
Environ. Entomol. |
pmid:18348793
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Moon DO et al. |
Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells. |
2008 |
Cancer Lett. |
pmid:18314260
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Sprogøe K et al. |
Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: levorotatory gossypol in Thespesia danis. |
2008 |
J. Nat. Prod. |
pmid:18290629
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Paoluzzi L et al. |
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma. |
2008 |
Blood |
pmid:18292288
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Przybylski P et al. |
CP/MAS spectroscopy in the determination of the tautomeric forms of gossypol, its Schiff bases and hydrazones in the solid state. |
2008 |
Magn Reson Chem |
pmid:18338327
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Zha SW et al. |
[Male antifertility drugs and cell apoptosis]. |
2008 |
Zhonghua Nan Ke Xue |
pmid:18297819
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RodrÃguez-EnrÃquez S et al. |
Energy metabolism transition in multi-cellular human tumor spheroids. |
2008 |
J. Cell. Physiol. |
pmid:18264981
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Arnold AA et al. |
Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model. |
2008 |
Mol. Cancer |
pmid:18275607
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Sikora MJ et al. |
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol. |
2008 |
Cancer Biol. Ther. |
pmid:18376141
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Dowd MK and Pelitire SM |
HPLC preparation of the chiral forms of 6-methoxy-gossypol and 6,6'-dimethoxy-gossypol. |
2008 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:18407810
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Marzo I and Naval J |
Bcl-2 family members as molecular targets in cancer therapy. |
2008 |
Biochem. Pharmacol. |
pmid:18638457
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Liu J et al. |
Stereoselective coupling of hemigossypol to form (+)-gossypol in moco cotton is mediated by a dirigent protein. |
2008 |
Phytochemistry |
pmid:18639908
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Villaseñor M et al. |
Gossypol disrupts embryo development in heifers. |
2008 |
J. Dairy Sci. |
pmid:18650278
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Aoyama K |
[Determination of gossypol in feeds by HPLC]. |
2008 |
Shokuhin Eiseigaku Zasshi |
pmid:18787315
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Sun Y et al. |
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo. |
2008 |
Cancer Biol. Ther. |
pmid:18769131
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Moon DO et al. |
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT. |
2008 |
FEBS Lett. |
pmid:18775705
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Przybylski P et al. |
Molecular structures and stability constants of gossypol and its aza-derivative complexes with silver(I) cations studied by potentiometric, ESI MS, NMR, and AM1d semiempirical methods. |
2008 |
J Phys Chem A |
pmid:18698745
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Boonsri S et al. |
Cytotoxic and antibacterial sesquiterpenes from Thespesia populnea. |
2008 |
J. Nat. Prod. |
pmid:18553924
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Zhou DR et al. |
Gossypol repressed the gap junctional intercellular communication between Sertoli cells by decreasing the expression of Connexin43. |
2008 |
Toxicol In Vitro |
pmid:18706992
|
Trischitta F and Faggio C |
Gossypol affects ion transport in the isolated intestine of the seawater adapted eel, Anguilla anguilla. |
2008 |
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. |
pmid:18606239
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Etxebarria A et al. |
Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems. |
2008 |
Biochem. Pharmacol. |
pmid:18762177
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Tang Y et al. |
[Progress in small-molecule inhibitors of Bcl-2 family proteins]. |
2008 |
Yao Xue Xue Bao |
pmid:18819468
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Gong YZ et al. |
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase. |
2008 |
Eur. J. Pharmacol. |
pmid:18930721
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Sun J et al. |
ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells. |
2008 |
Anticancer Drugs |
pmid:18827561
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Janssen CO et al. |
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18845435
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Karaca B et al. |
Profiling of angiogenic cytokines produced by hormone- and drug-refractory prostate cancer cell lines, PC-3 and DU-145 before and after treatment with gossypol. |
2008 |
Eur. Cytokine Netw. |
pmid:19103523
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Macoska JA et al. |
-(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro. |
2008 Nov-Dec |
Pharmacol. Res. |
pmid:18840529
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Sheweita SA et al. |
N-Nitrosodimethylamine changes the expression of glutathione S-transferase in the liver of male mice: The role of antioxidants. |
2008 Nov-Dec |
J. Biochem. Mol. Toxicol. |
pmid:19111000
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Zhai G et al. |
A liposomal delivery vehicle for the anticancer agent gossypol. |
2008 Sep-Oct |
Anticancer Res. |
pmid:19035313
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Pankajakshy A and Madambath I |
Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol. |
2009 |
Fertil. Steril. |
pmid:18692834
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Wei J et al. |
Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins. |
2009 |
Mol. Cancer Ther. |
pmid:19372563
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Xu WB et al. |
The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis. |
2009 |
Acta Pharmacol. Sin. |
pmid:19363517
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Zhan Y et al. |
Design and synthesis of a gossypol derivative with improved antitumor activities. |
2009 |
Arch. Pharm. (Weinheim) |
pmid:19340835
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Verma PC et al. |
Efficient production of gossypol from hairy root cultures of cotton (Gossypium hirsutum L.). |
2009 |
Curr Pharm Biotechnol |
pmid:19751178
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Sanli UA et al. |
Targeting apoptosis in the hormone- and drug-resistant prostate cancer cell line, DU-145, by gossypol/zoledronic acid combination. |
2009 |
Cell Biol. Int. |
pmid:19716895
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Das SG et al. |
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. |
2009 |
J. Med. Chem. |
pmid:19743858
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Hu ZY et al. |
ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
pmid:19698176
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Wang X et al. |
Gossypol--a polyphenolic compound from cotton plant. |
2009 |
Adv. Food Nutr. Res. |
pmid:19878861
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Atmaca H et al. |
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
|
Zerp SF et al. |
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. |
2009 |
Radiat Oncol |
pmid:19852810
|
Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
|
Wu G et al. |
Temporal allocation of metabolic tolerance in the body of beet armyworm in response to three gossypol-cotton cultivars. |
2009 |
Sci. China, C, Life Sci. |
pmid:20016971
|