Pankajakshy A and Madambath I |
Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol. |
2009 |
Fertil. Steril. |
pmid:18692834
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Wei J et al. |
Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists. |
2009 |
Cancer Lett. |
pmid:18782651
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Azmi AS and Mohammad RM |
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy. |
2009 |
J. Cell. Physiol. |
pmid:18767026
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Kang MH and Reynolds CP |
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. |
2009 |
Clin. Cancer Res. |
pmid:19228717
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Lin J et al. |
[Effect of apogossypolone on induction apoptosis in multiple myeloma cells and its mechanisms]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:19236755
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Przybylski P et al. |
Complexes of heterocyclic aza-derivatives of phytoalexin from cotton plant-gossypol with alkali metal cations and perchlorate anion studied by ESI mass spectrometric method in the positive and negative modes. |
2009 |
J Mass Spectrom |
pmid:19189269
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Przybylski P et al. |
Antifungal activity of alkyl and heterocyclic aza-derivatives of gossypol as well as their complexes with NaClO4 against Fusarium oxysporum f. sp. lupini. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19264482
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Hu ZY et al. |
ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
pmid:19698176
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Kilic A et al. |
Efficacy of signal pathway inhibitors alone and in combination with Cisplatin varies between human non-small cell lung cancer lines. |
2009 |
J. Surg. Res. |
pmid:19084241
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Chen BB et al. |
The (+)- and (-)-gossypols potently inhibit human and rat 11beta-hydroxysteroid dehydrogenase type 2. |
2009 |
J. Steroid Biochem. Mol. Biol. |
pmid:19150652
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Stipanovic RD et al. |
Total and percent atropisomers of gossypol and gossypol-6-methyl ether in seeds from pima cottons and accessions of Gossypium barbadense L. |
2009 |
J. Agric. Food Chem. |
pmid:19113939
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Zhang L et al. |
Chiral gossypol derivatives: evaluation of their anticancer activity and molecular modeling. |
2009 |
Eur J Med Chem |
pmid:19447525
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Sun J et al. |
Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. |
2009 |
Oncol. Rep. |
pmid:19513523
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Jiang J et al. |
Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling. |
2009 |
Int. J. Mol. Med. |
pmid:19513537
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Przybylski P et al. |
Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant--gossypol. |
2009 |
Eur J Med Chem |
pmid:19577825
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Wei J et al. |
Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2009 |
J. Med. Chem. |
pmid:19555126
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Lestini BJ et al. |
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists. |
2009 |
Cancer Biol. Ther. |
pmid:19556859
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Ionov M et al. |
The immobilization of gossypol derivative on N-polyvinylpyrrolidone increases its water solubility and modifies membrane-active properties. |
2009 |
J. Med. Chem. |
pmid:19603832
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Anilkumar KJ et al. |
Synergistic interactions between Cry1Ac and natural cotton defenses limit survival of Cry1Ac-resistant Helicoverpa zea (Lepidoptera: Noctuidae) on Bt cotton. |
2009 |
J. Chem. Ecol. |
pmid:19588197
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Huang YW et al. |
(-)-Gossypol reduces invasiveness in metastatic prostate cancer cells. |
2009 |
Anticancer Res. |
pmid:19528479
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Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
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Wu G et al. |
Temporal allocation of metabolic tolerance in the body of beet armyworm in response to three gossypol-cotton cultivars. |
2009 |
Sci. China, C, Life Sci. |
pmid:20016971
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Roychoudhury S et al. |
In vitro gossypol induced spermatozoa motility alterations in rabbits. |
2009 |
J Environ Sci Health B |
pmid:20183084
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Wang WQ et al. |
[Apoptosis of multiple myeloma cells induced by gossypol acetic acid in vitro and its mechanism]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:20030926
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Zhai G et al. |
A liposomal delivery vehicle for the anticancer agent gossypol. |
2008 Sep-Oct |
Anticancer Res. |
pmid:19035313
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Macoska JA et al. |
-(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro. |
2008 Nov-Dec |
Pharmacol. Res. |
pmid:18840529
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Sheweita SA et al. |
N-Nitrosodimethylamine changes the expression of glutathione S-transferase in the liver of male mice: The role of antioxidants. |
2008 Nov-Dec |
J. Biochem. Mol. Toxicol. |
pmid:19111000
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Meng Y et al. |
Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa. |
2008 |
Mol. Cancer Ther. |
pmid:18645028
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Li ZM et al. |
Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin's lymphoma cells. |
2008 |
Cancer Biol. Ther. |
pmid:17938578
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Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate. |
2008 |
Cancer Chemother. Pharmacol. |
pmid:17356822
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Inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. |
2008 |
Curr. Med. Chem. |
pmid:18220769
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Przybylski P et al. |
EI MS and ESI MS studies of the bisesquiterpene from cotton seeds: Gossypol and its Aza-derivatives. |
2008 |
J Mass Spectrom |
pmid:18200654
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Kitada S et al. |
Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048). |
2008 |
Blood |
pmid:18202226
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Arnold AA et al. |
Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model. |
2008 |
Mol. Cancer |
pmid:18275607
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Sikora MJ et al. |
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol. |
2008 |
Cancer Biol. Ther. |
pmid:18376141
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Dowd MK and Pelitire SM |
HPLC preparation of the chiral forms of 6-methoxy-gossypol and 6,6'-dimethoxy-gossypol. |
2008 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:18407810
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Ojha P et al. |
Rat testicular germ cell type(s) targeted by anti-spermatogenic agents in vivo and their recovery on withdrawal of treatment--a flow cytometric study. |
2008 |
Anim. Reprod. Sci. |
pmid:17207942
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Balakrishnan K et al. |
Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells. |
2008 |
Blood |
pmid:18566329
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Wang X et al. |
Bioactivities of gossypol, 6-methoxygossypol, and 6,6'-dimethoxygossypol. |
2008 |
J. Agric. Food Chem. |
pmid:18517219
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Johnson PW |
New targets for lymphoma treatment. |
2008 |
Ann. Oncol. |
pmid:18519406
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Marzo I and Naval J |
Bcl-2 family members as molecular targets in cancer therapy. |
2008 |
Biochem. Pharmacol. |
pmid:18638457
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Liu J et al. |
Stereoselective coupling of hemigossypol to form (+)-gossypol in moco cotton is mediated by a dirigent protein. |
2008 |
Phytochemistry |
pmid:18639908
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Trischitta F and Faggio C |
Gossypol affects ion transport in the isolated intestine of the seawater adapted eel, Anguilla anguilla. |
2008 |
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. |
pmid:18606239
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Tang Y et al. |
[Progress in small-molecule inhibitors of Bcl-2 family proteins]. |
2008 |
Yao Xue Xue Bao |
pmid:18819468
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Gong YZ et al. |
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase. |
2008 |
Eur. J. Pharmacol. |
pmid:18930721
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Sun J et al. |
ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells. |
2008 |
Anticancer Drugs |
pmid:18827561
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Janssen CO et al. |
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18845435
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Mi JX et al. |
Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma. |
2008 |
Acta Pharmacol. Sin. |
pmid:19026166
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Stipanovic RD et al. |
Effect of racemic, (+)- and (-)-gossypol on survival and development of Heliothis virescens larvae. |
2008 |
Environ. Entomol. |
pmid:19036185
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Karaca B et al. |
Profiling of angiogenic cytokines produced by hormone- and drug-refractory prostate cancer cell lines, PC-3 and DU-145 before and after treatment with gossypol. |
2008 |
Eur. Cytokine Netw. |
pmid:19103523
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