Dao VT et al. |
Synthesis and cytotoxicity of gossypol related compounds. |
2000 |
Eur J Med Chem |
pmid:11006482
|
El-Nassan HB |
Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents. |
2013 |
Eur J Med Chem |
pmid:23434636
|
Przybylski P et al. |
Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant--gossypol. |
2009 |
Eur J Med Chem |
pmid:19577825
|
Zhang Z et al. |
Novel soluble myeloid cell leukemia sequence 1 (Mcl-1) inhibitor (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile (4g) developed using a fragment-based approach. |
2013 |
Eur J Med Chem |
pmid:23220642
|
Zhang Z et al. |
Design and application of a rigid quinazolone scaffold based on two-face Bim α-helix mimicking. |
2013 |
Eur J Med Chem |
pmid:24095762
|
Zhang Z et al. |
Fragment-based design, synthesis, and biological evaluation of N-substituted-5-(4-isopropylthiophenol)-2-hydroxynicotinamide derivatives as novel Mcl-1 inhibitors. |
2013 |
Eur J Med Chem |
pmid:23314054
|
Zubair H et al. |
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage. |
2012 |
Eur J Pharm Sci |
pmid:22554693
|
Karaca B et al. |
Profiling of angiogenic cytokines produced by hormone- and drug-refractory prostate cancer cell lines, PC-3 and DU-145 before and after treatment with gossypol. |
2008 |
Eur. Cytokine Netw. |
pmid:19103523
|
Atmaca H et al. |
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
|
Medrano FJ and Andreu JM |
Binding of gossypol to purified tubulin and inhibition of its assembly into microtubules. |
1986 |
Eur. J. Biochem. |
pmid:3732269
|
Tripathi AK et al. |
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme. |
2004 |
Eur. J. Biochem. |
pmid:15317584
|
Spijkers-Hagelstein JA et al. |
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101. |
2014 |
Eur. J. Cancer |
pmid:24703900
|
Bai JP et al. |
Effects of demethylzeylasteral and celastrol on spermatogenic cell Ca2+ channels and progesterone-induced sperm acrosome reaction. |
2003 |
Eur. J. Pharmacol. |
pmid:12600689
|
Ye YX et al. |
Direct actions of gossypol on cardiac muscle. |
1987 |
Eur. J. Pharmacol. |
pmid:3036543
|
Kuhn G et al. |
Gossypol induces chloride secretion in rat proximal colon. |
2002 |
Eur. J. Pharmacol. |
pmid:12464365
|
Ye YX et al. |
Cardiodepressant actions of the orally active male contraceptive, gossypol, in guinea-pig heart muscle. |
1987 |
Eur. J. Pharmacol. |
pmid:3691653
|
Carruthers NJ et al. |
Gossypol inhibits calcineurin phosphatase activity at multiple sites. |
2007 |
Eur. J. Pharmacol. |
pmid:17141216
|
Alheid U et al. |
Human endothelial cells inhibit platelet aggregation by separately stimulating platelet cyclic AMP and cyclic GMP. |
1989 |
Eur. J. Pharmacol. |
pmid:2546782
|
Hervé JC et al. |
Contraceptive gossypol blocks cell-to-cell communication in human and rat cells. |
1996 |
Eur. J. Pharmacol. |
pmid:8911921
|
Gong YZ et al. |
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase. |
2008 |
Eur. J. Pharmacol. |
pmid:18930721
|
Dudel C and Förstermann U |
Gossypol attenuates selectively the blood pressure lowering effect of endothelium-dependent vasodilators in the rabbit in vivo. |
1988 |
Eur. J. Pharmacol. |
pmid:2450761
|
Mülsch A et al. |
Stimulation of soluble guanylate cyclase by endothelium-derived relaxing factor from cultured endothelial cells. |
1987 |
Eur. J. Pharmacol. |
pmid:2884122
|
Huang LH et al. |
Gossypol inhibits phosphorylation of Bcl-2 in human leukemia HL-60 cells. |
2010 |
Eur. J. Pharmacol. |
pmid:20633548
|
Bai J and Shi Y |
Inhibition of T-type Ca(2+) currents in mouse spermatogenic cells by gossypol, an antifertility compound. |
2002 |
Eur. J. Pharmacol. |
pmid:11959082
|
Pond GR et al. |
Evaluating the value of number of cycles of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer. |
2012 |
Eur. Urol. |
pmid:21715086
|
Shen Y and Ye D |
Re: Gregory R. Pond, Andrew J. Armstrong, Brian A. Wood, et al. Evaluating the value of number of cycles of docetaxel and prednisone in men with metastatic castration-resistant prostate cancer. Eur Urol 2012;61:363-9. |
2012 |
Eur. Urol. |
pmid:21824719
|
Qiu J et al. |
Different pathways of cell killing by gossypol enantiomers. |
2002 |
Exp. Biol. Med. (Maywood) |
pmid:12037129
|
Kline MP et al. |
R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. |
2008 |
Exp. Hematol. |
pmid:18346839
|
Javed MH and Khan MA |
Effect of amino acids on inhibition of lactate dehydrogenase-X by gossypol. |
1999 |
Exp. Mol. Med. |
pmid:10231019
|
Floridi A et al. |
The effect of gossypol and Lonidamine on electron transport in Ehrlich ascites tumor mitochondria. |
1984 |
Exp. Mol. Pathol. |
pmid:6705894
|
Floridi A et al. |
The effect of the association of Gossypol and Lonidamine on the energy metabolism of Ehrlich ascites tumor cells. |
1983 |
Exp. Mol. Pathol. |
pmid:6852206
|
Konac E et al. |
An in vitro study of cytotoxic effects of gossypol on human epidermoid larynx carcinoma cell line (HEp-2). |
2005 |
Exp. Oncol. |
pmid:15812364
|
Varol U et al. |
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers. |
2009 |
Exp. Oncol. |
pmid:20010531
|
Eid JE et al. |
Gossypol-induced death of African trypanosomes. |
1988 |
Exp. Parasitol. |
pmid:3366212
|
Rikihisa Y et al. |
Taenia taeniaeformis: inactivation of metacestodes by gossypol in vitro. |
1990 |
Exp. Parasitol. |
pmid:2373186
|
Rikihisa Y and Lin YC |
Taenia taeniaeformis: inhibition of metacestode development in the rat by gossypol. |
1986 |
Exp. Parasitol. |
pmid:3956677
|
Gonzalez-Garza MT and Said-Fernandez S |
Entamoeba histolytica: potent in vitro antiamoebic effect of gossypol. |
1988 |
Exp. Parasitol. |
pmid:2899518
|
Tone JN and Jensen DR |
The accumulation pattern of ingested gossypol in selected organs of the rat. |
1976 |
Experientia |
pmid:1253913
|
Tone JN and Jensen DR |
Effect of ingested gossypol on the growth performance of rats. |
1970 |
Experientia |
pmid:5478639
|
Abou-Donia MB et al. |
Gossypol: antagonistic effect on toxicity of insecticides to Spodoptera littoralis. |
1974 |
Experientia |
pmid:4435119
|
Manmade A et al. |
Gossypol. Synthesis and in vitro spermicidal activity of isomeric hemigossypol derivatives. |
1983 |
Experientia |
pmid:6641903
|
Dodou K et al. |
Investigations on gossypol: past and present developments. |
2005 |
Expert Opin Investig Drugs |
pmid:16255680
|
Goriunova LV and Vichkanova SA |
[Study of antiviral effect of gossypol on chick embryo model]. |
1969 Sep-Oct |
Farmakol Toksikol |
pmid:5364687
|
Lei X et al. |
Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. |
2006 |
FASEB J. |
pmid:16935937
|
Junco M et al. |
Substrate-dependent inhibition of protein kinase C by specific inhibitors. |
1990 |
FEBS Lett. |
pmid:2332048
|
Baker ME |
Gossypol inhibits estrogen binding to rat alpha-fetoprotein. |
1984 |
FEBS Lett. |
pmid:6207049
|
Moon DO et al. |
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT. |
2008 |
FEBS Lett. |
pmid:18775705
|
Royer RE and Vander Jagt DL |
Gossypol binds to a high-affinity binding site on human serum albumin. |
1983 |
FEBS Lett. |
pmid:6862017
|
VERMEL EM and KRUGLYAK SA |
ANTITUMOR ACTIVITY OF GOSSYPOL IN EXPERIMENTS ON TRANSPLANTABLE TUMORS. |
1965 Jan-Feb |
Fed Proc Transl Suppl |
pmid:14275562
|
Weissenmayer B et al. |
The calcineurin inhibitor gossypol impairs growth, cell signalling and development in Dictyostelium discoideum. |
2005 |
FEMS Microbiol. Lett. |
pmid:15621416
|