MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.
To understand associated biological information of Glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glycyrrhetinic acid is suspected in Hypertensive disease, Kozlowski Celermajer Tink syndrome, Hypernatremia, Leishmaniasis, Visceral, Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glycyrrhetinic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Ear Diseases | D004427 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yan G et al. | Preparation and evaluation of liver-targeting micelles loaded with oxaliplatin. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25287740 |
Wojciechowski K et al. | Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers. | 2016 | Biochim. Biophys. Acta | pmid:26654784 |
Papaevgeniou N et al. | 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures. | 2016 | Antioxid. Redox Signal. | pmid:26886723 |
Li Y et al. | Synthesis and Anticancer Activities of Glycyrrhetinic Acid Derivatives. | 2016 | Molecules | pmid:26861280 |
Yamada A et al. | Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. | 2016 | J. Biol. Chem. | pmid:26565022 |
Takeuchi R et al. | Possible pharmacotherapy for nifedipine-induced gingival overgrowth: 18α-glycyrrhetinic acid inhibits human gingival fibroblast growth. | 2016 | Br. J. Pharmacol. | pmid:26676684 |
Chen F et al. | Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA. | 2016 | Biomater Sci | pmid:26484363 |
Yan T et al. | Effective co-delivery of doxorubicin and curcumin using a glycyrrhetinic acid-modified chitosan-cystamine-poly(ε-caprolactone) copolymer micelle for combination cancer chemotherapy. | 2016 | Colloids Surf B Biointerfaces | pmid:27281238 |
Huang QC et al. | Can active components of licorice, glycyrrhizin and glycyrrhetinic acid, lick rheumatoid arthritis? | 2016 | Oncotarget | pmid:26498361 |
Zhang H et al. | Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor. | 2015 | Acta Pharmacol. Sin. | pmid:26279158 |