MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Falcarindiol is a lipid of Fatty Acyls (FA) class. Falcarindiol is associated with abnormalities such as Contact Dermatitis and Immune System Diseases. The involved functions are known as Delayed Hypersensitivity, Immune Tolerance, Stimulus, Metabolic Inhibition and Biochemical Pathway. Falcarindiol often locates in Cell surface, Abdomen and Bone Marrow. The associated genes with Falcarindiol are CD276 Antigen, VTCN1 gene, RELB gene, L1RE1 gene and ICOSLG gene. The related lipids are Lipopolysaccharides.
To understand associated biological information of Falcarindiol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Falcarindiol is suspected in Contact Dermatitis, Immune System Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Falcarindiol
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Falcarindiol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mitsui S et al. | The herbal medicine compound falcarindiol from Notopterygii Rhizoma suppresses dendritic cell maturation. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20215408 |
Meot-Duros L et al. | New antibacterial and cytotoxic activities of falcarindiol isolated in Crithmum maritimum L. leaf extract. | 2010 | Food Chem. Toxicol. | pmid:19922760 |
Vucković I et al. | A new prenylated flavanonol from Seseli annuum roots showing protective effect on human lymphocytes DNA. | 2010 | Chem. Biodivers. | pmid:20232332 |
Wang J et al. | [Fast determination of active components in Angelica dahurica extract using capillary electrochromatography with methacrylate ester-based monolithic columns]. | 2010 | Se Pu | pmid:20549974 |
Ohnuma T et al. | Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound. | 2010 | Toxicol. Appl. Pharmacol. | pmid:20026152 |
Purup S et al. | Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation. | 2009 | J. Agric. Food Chem. | pmid:19694436 |
Ohnuma T et al. | Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress. | 2009 | Arch. Biochem. Biophys. | pmid:19527678 |
Schmiech L et al. | Structure determination of bisacetylenic oxylipins in carrots (Daucus carota L.) and enantioselective synthesis of falcarindiol. | 2009 | J. Agric. Food Chem. | pmid:19845355 |
Ma Z et al. | Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors. | 2008 | Bioorg. Med. Chem. | pmid:18166466 |
Schinkovitz A et al. | Antimycobacterial polyacetylenes from Levisticum officinale. | 2008 | Phytother Res | pmid:18350523 |