Falcarindiol

Falcarindiol is a lipid of Fatty Acyls (FA) class. Falcarindiol is associated with abnormalities such as Contact Dermatitis and Immune System Diseases. The involved functions are known as Delayed Hypersensitivity, Immune Tolerance, Stimulus, Metabolic Inhibition and Biochemical Pathway. Falcarindiol often locates in Cell surface, Abdomen and Bone Marrow. The associated genes with Falcarindiol are CD276 Antigen, VTCN1 gene, RELB gene, L1RE1 gene and ICOSLG gene. The related lipids are Lipopolysaccharides.

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Introduction

To understand associated biological information of Falcarindiol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Falcarindiol?

Falcarindiol is suspected in Contact Dermatitis, Immune System Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Falcarindiol

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Falcarindiol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Falcarindiol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Falcarindiol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Falcarindiol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Falcarindiol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Falcarindiol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Falcarindiol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Falcarindiol

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Authors Title Published Journal PubMed Link
Mitsui S et al. The herbal medicine compound falcarindiol from Notopterygii Rhizoma suppresses dendritic cell maturation. 2010 J. Pharmacol. Exp. Ther. pmid:20215408
Meot-Duros L et al. New antibacterial and cytotoxic activities of falcarindiol isolated in Crithmum maritimum L. leaf extract. 2010 Food Chem. Toxicol. pmid:19922760
Vucković I et al. A new prenylated flavanonol from Seseli annuum roots showing protective effect on human lymphocytes DNA. 2010 Chem. Biodivers. pmid:20232332
Wang J et al. [Fast determination of active components in Angelica dahurica extract using capillary electrochromatography with methacrylate ester-based monolithic columns]. 2010 Se Pu pmid:20549974
Ohnuma T et al. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound. 2010 Toxicol. Appl. Pharmacol. pmid:20026152
Purup S et al. Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation. 2009 J. Agric. Food Chem. pmid:19694436
Ohnuma T et al. Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress. 2009 Arch. Biochem. Biophys. pmid:19527678
Schmiech L et al. Structure determination of bisacetylenic oxylipins in carrots (Daucus carota L.) and enantioselective synthesis of falcarindiol. 2009 J. Agric. Food Chem. pmid:19845355
Ma Z et al. Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors. 2008 Bioorg. Med. Chem. pmid:18166466
Schinkovitz A et al. Antimycobacterial polyacetylenes from Levisticum officinale. 2008 Phytother Res pmid:18350523