24(S),25-Epoxycholesterol

24(S),25-Epoxycholesterol is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 285 references associated with 24(S),25-Epoxycholesterol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with 24(S),25-Epoxycholesterol

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Authors Title Published Journal PubMed Link
Wong J et al. Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis. 2008 J. Biol. Chem. pmid:17981807
Ouimet M et al. Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux. 2008 Arterioscler. Thromb. Vasc. Biol. pmid:18369155
Cheng JF et al. Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators. 2008 J. Med. Chem. pmid:18324758
Wong J et al. Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. 2007 J. Neurochem. pmid:17956548
Duniec-Dmuchowski Z et al. Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists. 2007 Biochem. Pharmacol. pmid:17825266
Heverin M et al. Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol. 2007 Arterioscler. Thromb. Vasc. Biol. pmid:17761942
Zapata-Gonzalez F et al. 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. 2007 J. Immunol. pmid:17475839
Beyea MM et al. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. 2007 J. Biol. Chem. pmid:17186944
Wong J et al. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. 2006 Biochem. J. pmid:16901265
Li L et al. Discovery and optimization of a novel series of liver X receptor-alpha agonists. 2006 Bioorg. Med. Chem. Lett. pmid:16386417