| MeSH term | MeSH ID | Detail |
|---|---|---|
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
2
22-Hydroxycholesterol
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 22-Hydroxycholesterol?
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- J. Lipid Res. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Arterioscler. Thromb. Vasc. Biol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
PubChem Associated disorders and diseases
What pathways are associated with 22-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 22-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (3)
- Arterioscler. Thromb. Vasc. Biol. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Others (8)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 22-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 22-Hydroxycholesterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cheng J et al. | The inhibitory effects of manganese on steroidogenesis in rat primary Leydig cells by disrupting steroidogenic acute regulatory (StAR) protein expression. | 2003 | Toxicology | pmid:12699903 |
| Hsu CC et al. | Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis. | 2003 | FEBS Lett. | pmid:12753921 |
| Jabara S et al. | Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype. | 2003 | J. Clin. Endocrinol. Metab. | pmid:12519894 |
| Bortnick AE et al. | Identification and characterization of rodent ABCA1 in isolated type II pneumocytes. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12909583 |
| Ide T et al. | Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. | 2003 | Mol. Endocrinol. | pmid:12730332 |
| Koldamova RP et al. | 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion. | 2003 | J. Biol. Chem. | pmid:12547833 |
| Antonio V et al. | Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells. | 2003 | Biochem. J. | pmid:12882648 |
| Goodwin B et al. | Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha. | 2003 | Mol. Endocrinol. | pmid:12554795 |
| Kaneko E et al. | Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. | 2003 | J. Biol. Chem. | pmid:12847102 |
| Gouédard C et al. | Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins. | 2003 | Mol. Pharmacol. | pmid:12644596 |