Disease MeSH term: Xanthomatosis, Cerebrotendinous

Possible associated with:

Structure name description Reference count
TROLEANDOMYCIN TROLEANDOMYCIN is a lipid of Polyketides (PK) class. Troleandomycin is associated with abnormalities such as Xanthomatosis, Cerebrotendinous and Jaundice, Obstructive. The involved functions are known as Binding (Molecular Function), Anabolism, hydroxylase activity, Oxidation and immunoreactivity. Troleandomycin often locates in Microsomes, Liver, Human tissue, Microsomes, Hepatic and Immune system. The associated genes with TROLEANDOMYCIN are CYP3A5 gene, CYP3A7 gene, CYP2D6 gene, P4HTM gene and CYP2C19 gene. The related lipids are Androstenes, androstan-17-one, 25-hydroxycholesterol, Sterols and 4-hydroxycholesterol. 948
Cholic acid Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid. 3054
cholesterol cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. 98461
Dihydrocholesterol Dihydrocholesterol is a lipid of Sterol Lipids (ST) class. Dihydrocholesterol is associated with abnormalities such as Exanthema, Morphologically altered structure, protrusion, Dehydration and Xanthoma. The involved functions are known as Regulation, Biochemical Pathway, Methylation, Metabolic Inhibition and Biosynthetic Pathways. Dihydrocholesterol often locates in envelope, Mitochondria, Lipid Bilayers, Host Cell and Membrane. The associated genes with Dihydrocholesterol are GRAP2 gene, PTP4A2 gene, HSD3B7 gene, MBD2 gene and IGF2BP3 gene. The related lipids are Sterols, Cardiolipins, Pregnanes, 7-hydroxy-4-cholesten-3-one and Hydroxycholesterols. The related experimental models are Mouse Model. 281
Coprosterol Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model. 165
22-Hydroxycholesterol 22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol. 210
26-Hydroxycholesterol 26-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 26-hydroxycholesterol is associated with abnormalities such as Cardiovascular Diseases, Vascular Diseases, Metabolic syndrome, Obesity and Fatty Streak, Arterial. The involved functions are known as Oxidation, phospholipase activity, glucose metabolism, Binding (Molecular Function) and Regulation. 26-hydroxycholesterol often locates in Immune system, Body tissue, Extracellular, Protoplasm and Back. The associated genes with 26-Hydroxycholesterol are Homologous Gene, chylomicron remnant, Receptor Gene, Alleles and D3 compound. The related lipids are 27-hydroxycholesterol, Hydroxycholesterols, Lysophosphatidylcholines, Total cholesterol and Lipopolysaccharides. The related experimental models are Knock-out and Transgenic Model. 203
27-hydroxy-cholesterol(25R) 27-hydroxy-cholesterol(25r) is a lipid of Sterol Lipids (ST) class. 27-hydroxy-cholesterol(25r) is associated with abnormalities such as Consumption-archaic term for TB and Kozlowski Celermajer Tink syndrome. The involved functions are known as CYP27A1activity, mRNA Expression, Anabolism, Steroid biosynthesis and Metabolic Process, Cellular. 27-hydroxy-cholesterol(25r) often locates in Body tissue, soluble, Mitochondria and Inner mitochondrial membrane. The associated genes with 27-hydroxy-cholesterol(25R) are ABRA gene, IGKV1-16 gene, HSD3B1 gene, CYP21A2 gene and TSPO gene. The related lipids are Steroids and cholesterol analog. 183
Cholestenoic acid Cholestenoic acid is a lipid of Sterol Lipids (ST) class. Cholestenoic acid is associated with abnormalities such as Infection. The involved functions are known as Ligand Binding, Signal Pathways and Stereochemistry. Cholestenoic acid often locates in Blood. The associated genes with Cholestenoic acid are NCOA2 gene and P4HTM gene. The related lipids are cholestenoic acid and Sterols. 18
7alpha-Hydroxycholesterol 7alpha-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 7alpha-hydroxycholesterol is associated with abnormalities such as Atherosclerosis, Morphologically altered structure, Carotid Atherosclerosis, Myocardial Infarction and Cerebrovascular accident. The involved functions are known as Apoptosis, Cell Growth, Necrosis, Chromosome Condensation and Tissue Adhesions. 7alpha-hydroxycholesterol often locates in Arterial system, Endothelium, Cell Nucleus, Membrane and yolk. The associated genes with 7alpha-Hydroxycholesterol are acetyl-aspartyl-glutamyl-valyl-aspartal, BCL2 gene, OGFR gene, Genome and GAPDH gene. The related lipids are Hydroxycholesterols, 7-ketocholesterol, Ketocholesterols, 20-hydroxycholesterol and 25-hydroxycholesterol. 225
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