MeSH term | MeSH ID | Detail |
---|---|---|
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
Arteriosclerosis | D001161 | 86 associated lipids |
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
MeSH term | MeSH ID | Detail |
---|---|---|
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
Arteriosclerosis | D001161 | 86 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
López-Velázquez JA et al. | Nuclear receptors in nonalcoholic Fatty liver disease. | 2012 | J Lipids | pmid:22187655 |
Noguchi N | Role of oxidative stress in adaptive responses in special reference to atherogenesis. | 2008 | J Clin Biochem Nutr | pmid:19015746 |
Carter CJ | The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. | 2011 | ISRN Neurol | pmid:22389816 |
Norata GD et al. | Liver X receptor and retinoic X receptor agonists modulate the expression of genes involved in lipid metabolism in human endothelial cells. | 2005 | Int. J. Mol. Med. | pmid:16142410 |
Zhao SP et al. | Dual effects of oxidized low-density lipoprotein on LXR-ABCA1-apoA-I pathway in 3T3-L1 cells. | 2008 | Int. J. Cardiol. | pmid:17643522 |
Salehipour M et al. | Polyunsaturated fatty acids and modulation of cholesterol homeostasis in THP-1 macrophage-derived foam cells. | 2010 | Int J Mol Sci | pmid:21151462 |
Cacabelos R et al. | Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. | 2012 | Int J Alzheimers Dis | pmid:22482072 |
Patel MB et al. | Liver x receptor: a novel therapeutic target. | 2008 Mar-Apr | Indian J Pharm Sci | pmid:20046702 |
Gupta V | Mineralocorticoid hypertension. | 2011 | Indian J Endocrinol Metab | pmid:22145132 |
Yoon JH et al. | Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. | 2004 | Hepatology | pmid:14999691 |