22-Hydroxycholesterol

22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.

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Introduction

To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 22-Hydroxycholesterol?

22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol

MeSH term MeSH ID Detail
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Arteriosclerosis D001161 86 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with 22-Hydroxycholesterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 22-Hydroxycholesterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 22-Hydroxycholesterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 22-Hydroxycholesterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 22-Hydroxycholesterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 22-Hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 22-Hydroxycholesterol

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Authors Title Published Journal PubMed Link
Kase ET et al. Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals. 2007 Diabetologia pmid:17661008
Nazarov PA et al. Formation and functioning of fused cholesterol side-chain cleavage enzymes. 2003 DNA Cell Biol. pmid:12823901
Shenoy SD et al. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor. 2004 Drug Metab. Dispos. pmid:14709622
Cornejo Maciel F et al. Phosphotyrosine protein phosphatases activation by ACTH in rat adrenal gland. 1998 Aug-Nov Endocr. Res. pmid:9888510
Yu CC and Li PH In vivo inhibition of steroidogenic acute regulatory protein expression by dexamethasone parallels induction of the negative transcription factor DAX-1. 2006 Endocrine pmid:17526944
Lee JH et al. Androgen deprivation by activating the liver X receptor. 2008 Endocrinology pmid:18450964
Kolmakova A et al. Deficiency of scavenger receptor class B type I negatively affects progesterone secretion in human granulosa cells. 2010 Endocrinology pmid:20844007
Mauduit C et al. Tumor necrosis factor alpha inhibits gonadotropin action in cultured porcine Leydig cells: site(s) of action. 1991 Endocrinology pmid:1659519
Menke JG et al. A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a). 2002 Endocrinology pmid:12072387
Huang MC and Miller WL Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system. 2001 Endocrinology pmid:11356706