Yoshida K et al. |
Long-term feeding of hydroalcoholic extract powder of Lepidium meyenii (maca) enhances the steroidogenic ability of Leydig cells to alleviate its decline with ageing in male rats. |
2018 |
Andrologia |
pmid:28295471
|
Yi M et al. |
Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma. |
2017 |
Toxicol. Appl. Pharmacol. |
pmid:28729181
|
Li J et al. |
Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis. |
2017 |
Reprod. Biol. Endocrinol. |
pmid:28302174
|
Venugopal S et al. |
Plasma Membrane Origin of the Steroidogenic Pool of Cholesterol Used in Hormone-induced Acute Steroid Formation in Leydig Cells. |
2016 |
J. Biol. Chem. |
pmid:27815506
|
Kim H et al. |
22(R)-hydroxycholesterol induces HuR-dependent MAP kinase phosphatase-1 expression via mGluR5-mediated Ca(2+)/PKCα signaling. |
2016 |
Biochim. Biophys. Acta |
pmid:27206966
|
Ceroi A et al. |
The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation. |
2016 |
Haematologica |
pmid:26635040
|
Huwait EA et al. |
Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. |
2015 |
J. Cell. Biochem. |
pmid:25752819
|
Newby EA et al. |
Adrenocorticotropic Hormone and PI3K/Akt Inhibition Reduce eNOS Phosphorylation and Increase Cortisol Biosynthesis in Long-Term Hypoxic Ovine Fetal Adrenal Cortical Cells. |
2015 |
Reprod Sci |
pmid:25656500
|
Na TY et al. |
22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRα. |
2015 |
J. Pathol. |
pmid:25557254
|
Davydov R et al. |
Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies. |
2015 |
Biochemistry |
pmid:26603348
|
Trompier D et al. |
Regulation of the adrenoleukodystrophy-related gene (ABCD2): focus on oxysterols and LXR antagonists. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24480443
|
Wang JM et al. |
22(R)-hydroxycholesterol and pioglitazone synergistically decrease cholesterol ester via the PPARγ-LXRα-ABCA1 pathway in cholesterosis of the gallbladder. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24704452
|
Gondcaille C et al. |
LXR antagonists induce ABCD2 expression. |
2014 |
Biochim. Biophys. Acta |
pmid:24239766
|
Slominski AT et al. |
In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland. |
2014 |
Mol. Cell. Endocrinol. |
pmid:24382416
|
Soodgupta D et al. |
Modulation of LXR-α and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes. |
2014 |
Mol. Cell. Biochem. |
pmid:25283515
|
Mao D et al. |
ATF3 expression in the corpus luteum: possible role in luteal regression. |
2013 |
Mol. Endocrinol. |
pmid:24196350
|
Høgmoen Åstrand OA et al. |
(2S,3S)-2,6-dimethylheptane-1,3-diol, the oxygenated side chain of 22(S)-hydroxycholestrol, and its synthetic precursor (R)-4-benzyl-3-[(2R,3S)-3-hydroxy-2,6-dimethylheptanoyl]-1,3-oxazolidin-2-one. |
2013 |
Acta Crystallogr C |
pmid:23744388
|
Raccosta L et al. |
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils. |
2013 |
J. Exp. Med. |
pmid:23897983
|
Schaffer S et al. |
Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages. |
2013 |
Biochem. Pharmacol. |
pmid:23665353
|
Olala LO et al. |
A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models. |
2013 |
Mol. Cell. Endocrinol. |
pmid:23178798
|
El Roz A et al. |
LXR agonists and ABCG1-dependent cholesterol efflux in MCF-7 breast cancer cells: relation to proliferation and apoptosis. |
2012 |
Anticancer Res. |
pmid:22753765
|
Papadopoulos V and Lecanu L |
Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties. |
2012 |
J. Neuroendocrinol. |
pmid:21623958
|
Hessvik NP et al. |
The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism. |
2012 |
J. Steroid Biochem. Mol. Biol. |
pmid:22051079
|
Lecanu L et al. |
A steroid isolated from the water mold Achlya heterosexualis induces neurogenesis in vitro and in vivo. |
2012 |
Steroids |
pmid:22138207
|
Li W et al. |
Establishment and evaluation of a stable steroidogenic caprine luteal cell line. |
2012 |
Theriogenology |
pmid:22578611
|
GarcÃa MM et al. |
Cisplatin inhibits testosterone synthesis by a mechanism that includes the action of reactive oxygen species (ROS) at the level of P450scc. |
2012 |
Chem. Biol. Interact. |
pmid:22940207
|
Kittayaruksakul S et al. |
Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule. |
2012 |
Am. J. Physiol. Renal Physiol. |
pmid:22169006
|
Tranheim Kase E et al. |
Dietary supplementation with 22-S-hydroxycholesterol to rats reduces body weight gain and the accumulation of liver triacylglycerol. |
2012 |
Lipids |
pmid:22426832
|
Valbuena-Diez AC et al. |
Oxysterol-induced soluble endoglin release and its involvement in hypertension. |
2012 |
Circulation |
pmid:23110859
|
Soodvilai S et al. |
Liver X receptor agonists decrease ENaC-mediated sodium transport in collecting duct cells. |
2012 |
Am. J. Physiol. Renal Physiol. |
pmid:23077096
|
Kumar R et al. |
Altered levels of LXR-α: crucial implications in the pathogenesis of vitiligo. |
2012 |
Exp. Dermatol. |
pmid:23163651
|
López-Velázquez JA et al. |
Nuclear receptors in nonalcoholic Fatty liver disease. |
2012 |
J Lipids |
pmid:22187655
|
Nader N et al. |
Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism. |
2012 |
PLoS ONE |
pmid:22457708
|
Tsui KH et al. |
Molecular Mechanism of Isocupressic Acid Supresses MA-10 Cell Steroidogenesis. |
2012 |
Evid Based Complement Alternat Med |
pmid:22666287
|
Cacabelos R et al. |
Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. |
2012 |
Int J Alzheimers Dis |
pmid:22482072
|
Xue J et al. |
[Endothelial dysfunction induced by high glucose is associated with decreased ATP-binding cassette transporter G1 expression]. |
2012 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:22365996
|
Lin HP et al. |
Caffeic acid phenethyl ester causes p21 induction, Akt signaling reduction, and growth inhibition in PC-3 human prostate cancer cells. |
2012 |
PLoS ONE |
pmid:22347457
|
Ortega I et al. |
Simvastatin reduces steroidogenesis by inhibiting Cyp17a1 gene expression in rat ovarian theca-interstitial cells. |
2012 |
Biol. Reprod. |
pmid:21918126
|
Joo SH et al. |
Biosynthesis of a cholesterol-derived brassinosteroid, 28-norcastasterone, in Arabidopsis thaliana. |
2012 |
J. Exp. Bot. |
pmid:22170941
|
Amemiya-Kudo M et al. |
Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c). |
2011 |
J. Biol. Chem. |
pmid:21652712
|
Cruz-Garcia L et al. |
Regulation of LXR by fatty acids, insulin, growth hormone and tumor necrosis factor-α in rainbow trout myocytes. |
2011 |
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. |
pmid:21635958
|
Mast N et al. |
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. |
2011 |
J. Biol. Chem. |
pmid:21159775
|
Iborra RT et al. |
Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. |
2011 |
Lipids Health Dis |
pmid:21957962
|
Escobar JC et al. |
The human placenta expresses CYP17 and generates androgens de novo. |
2011 |
J. Clin. Endocrinol. Metab. |
pmid:21307141
|
Mastrocola R et al. |
Dysregulation of SREBP2 induces BACE1 expression. |
2011 |
Neurobiol. Dis. |
pmid:21726644
|
Huwait EA et al. |
A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression. |
2011 |
Cell. Signal. |
pmid:21070853
|
Aye IL et al. |
Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors. |
2011 |
Placenta |
pmid:21208656
|
Girard E et al. |
The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages. |
2011 |
PLoS ONE |
pmid:22205993
|
Chuu CP et al. |
Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer. |
2011 |
J. Biomed. Sci. |
pmid:21859492
|
Gupta V |
Mineralocorticoid hypertension. |
2011 |
Indian J Endocrinol Metab |
pmid:22145132
|