| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
Total
2
22-Hydroxycholesterol
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 22-Hydroxycholesterol?
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- J. Lipid Res. (2)
- J. Pharmacol. Exp. Ther. (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
PubChem Associated disorders and diseases
What pathways are associated with 22-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 22-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
- J. Biol. Chem. (3)
- Am. J. Physiol. Renal Physiol. (2)
- Arterioscler. Thromb. Vasc. Biol. (2)
- Others (9)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 22-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 22-Hydroxycholesterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Malerød L et al. | Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12470667 |
| Yao ZX et al. | 22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide. | 2002 | J. Neurochem. | pmid:12437582 |
| Bollag WB et al. | Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells. | 2002 | Mol. Cell. Endocrinol. | pmid:12088862 |
| Goldman JM and Murr AS | Alterations in ovarian follicular progesterone secretion by elevated exposures to the drinking water disinfection by-product dibromoacetic acid: examination of the potential site(s) of impact along the steroidogenic pathway. | 2002 | Toxicology | pmid:11836015 |
| Nishida Y et al. | Expression and functional analyses of novel mutations of ATP-binding cassette transporter-1 in Japanese patients with high-density lipoprotein deficiency. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11785958 |
| Menke JG et al. | A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a). | 2002 | Endocrinology | pmid:12072387 |
| Stein O et al. | Macrophage cholesterol efflux to free apoprotein A-I in C3H and C57BL/6 mice. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11820773 |
| Wu CS et al. | Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells. | 2001 Mar-Apr | J. Androl. | pmid:11229798 |
| Yoshikawa T et al. | Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. | 2001 | Mol. Cell. Biol. | pmid:11287605 |
| Fu X et al. | 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. | 2001 | J. Biol. Chem. | pmid:11504730 |
| Gan X et al. | Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate. | 2001 | J. Biol. Chem. | pmid:11641412 |
| Laffitte BA et al. | LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11149950 |
| DeBose-Boyd RA et al. | Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11171976 |
| Spencer TA et al. | Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. | 2001 | J. Med. Chem. | pmid:11300870 |
| Chiang JY et al. | Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha). | 2001 | Gene | pmid:11179691 |
| Liu MY et al. | The inhibitory effects of lead on steroidogenesis in MA-10 mouse Leydig tumor cells. | 2001 | Life Sci. | pmid:11213355 |
| Lorkowski S et al. | Genomic sequence and structure of the human ABCG1 (ABC8) gene. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11162488 |
| Tu AY and Albers JJ | Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11573953 |
| Jezová M et al. | Luteinization factor-stimulated steroidogenesis in porcine granulosa cells. | 2001 | Gen. Physiol. Biophys. | pmid:11519688 |
| Huang MC and Miller WL | Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system. | 2001 | Endocrinology | pmid:11356706 |