MeSH term | MeSH ID | Detail |
---|---|---|
Arteriosclerosis | D001161 | 86 associated lipids |
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
MeSH term | MeSH ID | Detail |
---|---|---|
Arteriosclerosis | D001161 | 86 associated lipids |
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Li W et al. | Establishment and evaluation of a stable steroidogenic caprine luteal cell line. | 2012 | Theriogenology | pmid:22578611 |
Lecanu L et al. | Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity. | 2004 | Steroids | pmid:14715372 |
Lecanu L et al. | A steroid isolated from the water mold Achlya heterosexualis induces neurogenesis in vitro and in vivo. | 2012 | Steroids | pmid:22138207 |
Khanna A et al. | Heat shock protein induction blocks hormone-sensitive steroidogenesis in rat luteal cells. | 1994 | Steroids | pmid:8140601 |
Piraino G et al. | Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages. | 2006 | Shock | pmid:16878022 |
Saito Y and Inada Y | [Lysis of plasma membrane by a unique oxygenated sterol: 22R-hydroxycholesterol]. | 1985 | Seikagaku | pmid:3831128 |
Crisafulli C et al. | Effects of Liver x receptor agonist treatment on signal transduction pathways in acute lung inflammation. | 2010 | Respir. Res. | pmid:20175894 |
Chen J et al. | Effects of fenvalerate on progesterone production in cultured rat granulosa cells. | 2005 Jul-Aug | Reprod. Toxicol. | pmid:15907653 |
Supornsilchai V et al. | Sesquiterpene lactone helenalin suppresses Leydig and adrenocortical cell steroidogenesis by inhibiting expression of the steroidogenic acute regulatory protein. | 2006 | Reprod. Toxicol. | pmid:16777379 |
Murono EP et al. | Octylphenol inhibits testosterone biosynthesis by cultured precursor and immature Leydig cells from rat testes. | 2000 May-Jun | Reprod. Toxicol. | pmid:10838129 |