| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
Total
2
22-Hydroxycholesterol
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 22-Hydroxycholesterol?
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
PubChem Associated disorders and diseases
What pathways are associated with 22-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 22-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 22-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 22-Hydroxycholesterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mastrocola R et al. | Dysregulation of SREBP2 induces BACE1 expression. | 2011 | Neurobiol. Dis. | pmid:21726644 |
| Lee CS et al. | Oxysterols suppress inducible nitric oxide synthase expression in lipopolysaccharide-stimulated astrocytes through liver X receptor. | 2006 | Neuroreport | pmid:16407768 |
| Yao ZX et al. | 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells. | 2007 | Neuroscience | pmid:17689017 |
| Patel NV and Forman BM | Linking lipids, Alzheimer's and LXRs? | 2004 | Nucl Recept Signal | pmid:16604185 |
| Weedon-Fekjaer MS et al. | Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line. | 2005 | Placenta | pmid:16226121 |
| Aye IL et al. | Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors. | 2011 | Placenta | pmid:21208656 |
| Matyash V et al. | Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. | 2004 | PLoS Biol. | pmid:15383841 |
| Albergotti LC et al. | Endocrine activity of extraembryonic membranes extends beyond placental amniotes. | 2009 | PLoS ONE | pmid:19424488 |
| Nader N et al. | Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism. | 2012 | PLoS ONE | pmid:22457708 |
| Flück CE et al. | Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia. | 2011 | PLoS ONE | pmid:21647419 |