MeSH term | MeSH ID | Detail |
---|---|---|
Arteriosclerosis | D001161 | 86 associated lipids |
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
MeSH term | MeSH ID | Detail |
---|---|---|
Arteriosclerosis | D001161 | 86 associated lipids |
Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sugano S et al. | Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: accumulation of the intermediate modulated by the adrenodoxin level. | 1996 | J. Biochem. | pmid:8947841 |
Doris PA et al. | Ouabain production by cultured adrenal cells. | 1996 | Endocrinology | pmid:8593799 |
Pezzi V et al. | Role of calmodulin-dependent protein kinase II in the acute stimulation of aldosterone production. | 1996 | J. Steroid Biochem. Mol. Biol. | pmid:8903426 |
Hawi SR et al. | Raman microspectroscopy of intracellular cholesterol crystals in cultured bovine coronary artery endothelial cells. | 1997 | J. Lipid Res. | pmid:9300781 |
Lala DS et al. | Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9144161 |
Marinero MJ et al. | Specific effect of arachidonic acid on 17beta-hydroxysteroid dehydrogenase in rat Leydig cells. | 1998 | FEBS Lett. | pmid:9475159 |
Lin T et al. | Interferon-gamma inhibits the steroidogenic acute regulatory protein messenger ribonucleic acid expression and protein levels in primary cultures of rat Leydig cells. | 1998 | Endocrinology | pmid:9564825 |
Lin T et al. | Interleukin-1 inhibits Leydig cell steroidogenesis without affecting steroidogenic acute regulatory protein messenger ribonucleic acid or protein levels. | 1998 | J. Endocrinol. | pmid:9582502 |
Bosc MJ and Nicolle A | Androstenedione and progesterone production in vitro by the inner or the outer theca cells in preovulatory follicles of gonadotropin stimulated calves. | 1998 | Anim. Reprod. Sci. | pmid:9672665 |
Dirami G and Cooke BA | Effect of a dopamine agonist on luteinizing hormone receptors, cyclic AMP production and steroidogenesis in rat Leydig cells. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9653071 |