| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
Total
2
22-Hydroxycholesterol
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 22-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 22-Hydroxycholesterol?
22-Hydroxycholesterol is suspected in Atherosclerosis, Fatty Streak, Arterial, Senile Plaques, Neurodegenerative Disorders, Coronary heart disease, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- J. Lipid Res. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Arterioscler. Thromb. Vasc. Biol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 22-Hydroxycholesterol
PubChem Associated disorders and diseases
What pathways are associated with 22-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 22-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
- J. Biol. Chem. (3)
- Am. J. Physiol. Renal Physiol. (2)
- Arterioscler. Thromb. Vasc. Biol. (2)
- Others (9)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 22-Hydroxycholesterol?
Related references are published most in these journals:
- J. Biol. Chem. (3)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (7)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 22-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 22-Hydroxycholesterol
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|---|---|---|---|---|
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| Calayir E et al. | LXR-agonists regulate ApoM expression differentially in liver and intestine. | 2008 | Curr Pharm Biotechnol | pmid:19075690 |
| Potocka A and Zimowski J | Metabolism of conjugated sterols in eggplant. Part 1. UDP-glucose : sterol glucosyltransferase. | 2008 | Acta Biochim. Pol. | pmid:18196184 |
| Hong X et al. | Effects of trichlorfon on progesterone production in cultured human granulosa-lutein cells. | 2007 | Toxicol In Vitro | pmid:17329077 |
| Wang YB et al. | Monobutyl phthalate inhibits steroidogenesis by downregulating steroidogenic acute regulatory protein expression in mouse Leydig tumor cells (MLTC-1). | 2007 | J. Toxicol. Environ. Health Part A | pmid:17479410 |
| Yao ZX et al. | 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells. | 2007 | Neuroscience | pmid:17689017 |
| Kase ET et al. | Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals. | 2007 | Diabetologia | pmid:17661008 |
| Grenier E et al. | Effect of retinoic acid on cell proliferation and differentiation as well as on lipid synthesis, lipoprotein secretion, and apolipoprotein biogenesis. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17916647 |
| Yu BL et al. | [Effects of oxidized low-density lipoprotein on cholesterol efflux in 3T3-L1 cells]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17767055 |
| Saldanha T and Bragagnolo N | Cholesterol oxidation is increased and PUFA decreased by frozen storage and grilling of Atlantic hake fillets (Merluccius hubbsi). | 2007 | Lipids | pmid:17492472 |
| Yan D et al. | Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17478758 |