Björkhem I |
Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. |
2006 |
J. Intern. Med. |
pmid:17116000
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Pikuleva IA |
Cholesterol-metabolizing cytochromes P450. |
2006 |
Drug Metab. Dispos. |
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Klass DM et al. |
Biliary lipids, cholesterol and bile synthesis: different adaptive mechanisms to dietary cholesterol in lean and obese subjects. |
2006 |
Aliment. Pharmacol. Ther. |
pmid:16573792
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Rojo L et al. |
Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. |
2006 |
J. Biomed. Biotechnol. |
pmid:17047312
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Kummerow FA et al. |
27-Hydroxycholesterol causes remodeling in endothelial cell membrane lipid composition comparable to remodeling in the failed vein grafts of CABG patients. |
2006 |
Life Sci. |
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Chen W et al. |
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. |
2007 |
Cell Metab. |
pmid:17189208
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Hojo K et al. |
Determination of total cholesterol in serum by high-performance liquid chromatography with electrochemical detection. |
2007 |
J Chromatogr A |
pmid:17723233
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Meaney S et al. |
Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid. |
2007 |
J. Lipid Res. |
pmid:17251592
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Gueguen Y et al. |
Compared effect of immunosuppressive drugs cyclosporine A and rapamycin on cholesterol homeostasis key enzymes CYP27A1 and HMG-CoA reductase. |
2007 |
Basic Clin. Pharmacol. Toxicol. |
pmid:17516993
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Li T et al. |
PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine. |
2007 |
J. Lipid Res. |
pmid:17088262
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Teunissen CE et al. |
24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis. |
2007 |
J. Neurosci. Res. |
pmid:17410599
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Hansson M et al. |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
2007 |
J. Intern. Med. |
pmid:17444890
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Jiang X et al. |
Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine. |
2007 |
Rapid Commun. Mass Spectrom. |
pmid:17154356
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Burkard I et al. |
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. |
2007 |
Atherosclerosis |
pmid:17107679
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Luomala M et al. |
Osteopontin levels are associated with cholesterol synthesis markers in mildly hypercholesterolaemic patients. |
2007 |
Acta Cardiol |
pmid:17536607
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Crosignani A et al. |
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease. |
2007 |
Clin. Chim. Acta |
pmid:17482152
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Li X et al. |
Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes. |
2007 |
J. Lipid Res. |
pmid:17890683
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Umetani M et al. |
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. |
2007 |
Nat. Med. |
pmid:17873880
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van den Bosch HM et al. |
Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting. |
2007 |
BMC Genomics |
pmid:17683626
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Mosig S et al. |
Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism. |
2008 |
BMC Med Genomics |
pmid:19040724
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de Vogel-van den Bosch HM et al. |
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:18356535
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Weiner MF et al. |
Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury. |
2008 |
Brain Inj |
pmid:18568715
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Ghribi O |
Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle. |
2008 |
J. Alzheimers Dis. |
pmid:19096164
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Cheng D et al. |
Regulation of alpha-synuclein expression by liver X receptor ligands in vitro. |
2008 |
Neuroreport |
pmid:18841091
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Lange Y et al. |
Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. |
2008 |
J. Biol. Chem. |
pmid:18024962
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Zhang JR et al. |
Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking. |
2008 |
J. Clin. Invest. |
pmid:18483620
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DuSell CD et al. |
27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. |
2008 |
Mol. Endocrinol. |
pmid:17872378
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Crosignani A et al. |
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis. |
2008 |
Clin. Chim. Acta |
pmid:18538136
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Lee CY et al. |
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample. |
2008 |
Free Radic. Biol. Med. |
pmid:18226605
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Rantham Prabhakara JP et al. |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. |
2008 |
J. Neurochem. |
pmid:19014385
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Yoshida T et al. |
Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. |
2008 |
Anal Chem Insights |
pmid:19609389
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Griffiths WJ et al. |
Discovering oxysterols in plasma: a window on the metabolome. |
2008 |
J. Proteome Res. |
pmid:18605750
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Sharma S et al. |
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. |
2008 |
Neurobiol. Dis. |
pmid:18775495
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DuSell CD and McDonnell DP |
27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling. |
2008 |
Trends Pharmacol. Sci. |
pmid:18722677
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DiBlasio-Smith EA et al. |
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells. |
2008 |
J Transl Med |
pmid:18925943
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Szatmari I and Nagy L |
Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function. |
2008 |
EMBO J. |
pmid:18716631
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Duron E and Hanon O |
Vascular risk factors, cognitive decline, and dementia. |
2008 |
Vasc Health Risk Manag |
pmid:18561512
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Patel MB et al. |
Liver x receptor: a novel therapeutic target. |
2008 Mar-Apr |
Indian J Pharm Sci |
pmid:20046702
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Tang W et al. |
Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzyme. |
2008 Nov-Dec |
Biochim. Biophys. Acta |
pmid:18817892
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Riendeau V and Garenc C |
Effect of 27-hydroxycholesterol on survival and death of human macrophages and vascular smooth muscle cells. |
2009 |
Free Radic. Res. |
pmid:19672739
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Olkkonen VM and Hynynen R |
Interactions of oxysterols with membranes and proteins. |
2009 |
Mol. Aspects Med. |
pmid:19248802
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Gilardi F et al. |
Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling. |
2009 |
Neuroscience |
pmid:19665519
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Lütjohann D et al. |
4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. |
2009 |
Int J Clin Pharmacol Ther |
pmid:19954708
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Zhou C et al. |
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. |
2009 |
Nucl Recept Signal |
pmid:19240808
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Prasanthi JR et al. |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. |
2009 |
Mol Neurodegener |
pmid:19126211
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Solomon A et al. |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. |
2009 |
Neurosci. Lett. |
pmid:19560513
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Honda A et al. |
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. |
2009 |
J. Lipid Res. |
pmid:18815436
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Morello F et al. |
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. |
2009 |
Atherosclerosis |
pmid:19426978
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Björkhem I et al. |
Oxysterols and neurodegenerative diseases. |
2009 |
Mol. Aspects Med. |
pmid:19248803
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Seet RC et al. |
Oxidative damage in dengue fever. |
2009 |
Free Radic. Biol. Med. |
pmid:19427377
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