Dihydrocholesterol is a lipid of Sterol Lipids (ST) class. Dihydrocholesterol is associated with abnormalities such as Exanthema, Morphologically altered structure, protrusion, Dehydration and Xanthoma. The involved functions are known as Regulation, Biochemical Pathway, Methylation, Metabolic Inhibition and Biosynthetic Pathways. Dihydrocholesterol often locates in envelope, Mitochondria, Lipid Bilayers, Host Cell and Membrane. The associated genes with Dihydrocholesterol are GRAP2 gene, PTP4A2 gene, HSD3B7 gene, MBD2 gene and IGF2BP3 gene. The related lipids are Sterols, Cardiolipins, Pregnanes, 7-hydroxy-4-cholesten-3-one and Hydroxycholesterols. The related experimental models are Mouse Model.
To understand associated biological information of Dihydrocholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrocholesterol is suspected in Xanthoma, Xanthomatosis, Cerebrotendinous, Coronary heart disease, Exanthema, Morphologically altered structure, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Dihydrocholesterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Brain Diseases, Metabolic | D001928 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase.' (BÃ¥vner A et al., 2010).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| VAN DER LINDEN W | ON GALLSTONE FORMATION IN RABBITS INDUCED BY DIHYDROCHOLESTEROL. 2. INFLUENCE OF OLIVE OIL IN THE DIET. | 1965 | Acta Chir Scand | pmid:14296589 |
| BORGSTROEM S et al. | ON GALLSTONE FORMATION IN RABBITS INDUCED BY DIHYDROCHOLESTEROL. | 1963 | Acta Chir Scand | pmid:14070605 |
| Lindelöf G and Van der Linden W | The role of stasis in experimental gallstone formation. | 1965 | Acta Chir Scand | pmid:5324759 |
| Canelas HM et al. | Cerebrotendinous xanthomatosis: clinical and laboratory study of 2 cases. | 1983 | Acta Neurol. Scand. | pmid:6410671 |
| van Heijst AF et al. | Chronic diarrhoea as a dominating symptom in two children with cerebrotendinous xanthomatosis. | 1996 | Acta Paediatr. | pmid:8863874 |
| PRANGE I et al. | Bacterial conversion of cholesterol into coprostanol independent of cerebrosides in the medium. | 1958 | Acta Pathol Microbiol Scand | pmid:13508244 |
| Gustafsson BE and Norin KE | Development of germfree animal characteristics in conventional rats in antibiotics. | 1977 | Acta Pathol Microbiol Scand B | pmid:320818 |
| Kay RM and Truswell AS | Effect of citrus pectin on blood lipids and fecal steroid excretion in man. | 1977 | Am. J. Clin. Nutr. | pmid:319647 |
| Gallo-Torres HE et al. | Some effects of deoxycholate administration on the metabolism of cholesterol in man. | 1979 | Am. J. Clin. Nutr. | pmid:377936 |