Dihydrocholesterol is a lipid of Sterol Lipids (ST) class. Dihydrocholesterol is associated with abnormalities such as Exanthema, Morphologically altered structure, protrusion, Dehydration and Xanthoma. The involved functions are known as Regulation, Biochemical Pathway, Methylation, Metabolic Inhibition and Biosynthetic Pathways. Dihydrocholesterol often locates in envelope, Mitochondria, Lipid Bilayers, Host Cell and Membrane. The associated genes with Dihydrocholesterol are GRAP2 gene, PTP4A2 gene, HSD3B7 gene, MBD2 gene and IGF2BP3 gene. The related lipids are Sterols, Cardiolipins, Pregnanes, 7-hydroxy-4-cholesten-3-one and Hydroxycholesterols. The related experimental models are Mouse Model.
To understand associated biological information of Dihydrocholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dihydrocholesterol is suspected in Xanthoma, Xanthomatosis, Cerebrotendinous, Coronary heart disease, Exanthema, Morphologically altered structure, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Dihydrocholesterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Brain Diseases, Metabolic | D001928 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase.' (BÃ¥vner A et al., 2010).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Inoue K et al. | Cholestanol induces apoptosis of cerebellar neuronal cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10066446 |
| Fadden K et al. | Steroid metabolism along the gastrointestinal tract of the cannulated pig. | 1999 | Eur. J. Cancer Prev. | pmid:10091041 |
| Gylling H et al. | Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population. | 1999 | J. Lipid Res. | pmid:10191283 |
| Uchida K et al. | Transformation of bile acids and sterols by clostridia (fusiform bacteria) in Wistar rats. | 1999 | Lipids | pmid:10230721 |
| Batta AK et al. | Highly simplified method for gas-liquid chromatographic quantitation of bile acids and sterols in human stool. | 1999 | J. Lipid Res. | pmid:10357847 |
| Panda SK et al. | Correlation of neomycin, faecal neutral and acid sterols with colon carcinogenesis in rats. | 1999 | Br. J. Cancer | pmid:10376962 |
| Radhakrishnan A and McConnell HM | Condensed complexes of cholesterol and phospholipids. | 1999 | Biophys. J. | pmid:10465761 |
| Fernandes MB et al. | Sedimentary 4-desmethyl sterols and n-alkanols in an eutrophic urban estuary, Capibaribe River, Brazil. | 1999 | Sci. Total Environ. | pmid:10466230 |
| Larking PW | Cancer and low levels of plasma cholesterol: the relevance of cholesterol precursors and products to incidence of cancer. | 1999 | Prev Med | pmid:10564630 |