Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.
To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Coprosterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Brain Diseases, Metabolic | D001928 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Brunnekreeft JW et al. | Direct determination of total serum cholesterol by on-column gas-liquid chromatographic analysis without previous derivatisation compared with WHO-CDC reference method. | 1983 | Ann. Clin. Biochem. | pmid:6418055 |
| Koopman BJ et al. | Capillary gas chromatographic determination of cholestanol/cholesterol ratio in biological fluids. Its potential usefulness for the follow-up of some liver diseases and its lack of specificity in diagnosing CTX (cerebrotendinous xanthomatosis). | 1984 | Clin. Chim. Acta | pmid:6421514 |
| Nair PP et al. | Diet, nutrition intake, and metabolism in populations at high and low risk for colon cancer. Metabolism of neutral sterols. | 1984 | Am. J. Clin. Nutr. | pmid:6435444 |
| Mott GE and Jackson EM | Loss of tritium from coprostanone derived from [1,2(n)-3H]cholesterol or [7(n)-3H]cholesterol. | 1980 | J. Lipid Res. | pmid:6770018 |
| Buttke TM et al. | Effect of sterol side chains on growth and membrane fatty acid composition of Saccharomyces cerevisiae. | 1980 | J. Bacteriol. | pmid:6774959 |
| Elliott WH | Identification of sterols and bile acids by computerized gas chromatography-mass spectrometry. | 1980 | Lipids | pmid:6775165 |
| Henderson GR and St Clair RW | Sources of error in the isotopic cholesterol balance method in African green monkeys consuming a cholesterol-free diet. | 1980 | J. Lipid Res. | pmid:6777440 |
| Mott GE et al. | Biochemical characterization of cholesterol-reducing Eubacterium. | 1980 | Appl. Environ. Microbiol. | pmid:6779702 |
| Janssen G and Parmentier G | A further study of the bile acids in infants with coprostanic acidemia. | 1981 | Steroids | pmid:6784283 |
| Lee SP | Hypersecretion of mucus glycoprotein by the gallbladder epithelium in experimental cholelithiasis. | 1981 | J. Pathol. | pmid:6790685 |