Coprosterol

Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.

Cross Reference

Introduction

To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprosterol?

Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coprosterol

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cataract D002386 34 associated lipids
Alcoholism D000437 27 associated lipids
Xanthomatosis D014973 17 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Biliary Fistula D001658 13 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Total 9

PubChem Associated disorders and diseases

What pathways are associated with Coprosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coprosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprosterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Coprosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprosterol?

Rodent Model

Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Coprosterol

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Authors Title Published Journal PubMed Link
Sperhake JP and Matschke J [Cerebrotendinous xanthomatosis--a treatable metabolic disorder]. 2004 Nervenarzt pmid:15257383
Ohgami N et al. Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15314240
Dotti MT et al. Normalisation of serum cholestanol concentration in a patient with cerebrotendinous xanthomatosis by combined treatment with chenodeoxycholic acid, simvastatin and LDL apheresis. 2004 Neurol. Sci. pmid:15549503
Keller S and Jahreis G Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces. 2004 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15556534
Veiga P et al. Correlation between faecal microbial community structure and cholesterol-to-coprostanol conversion in the human gut. 2005 FEMS Microbiol. Lett. pmid:15621423
Dantas-Leite L et al. Antiproliferative synergism of azasterols and antifolates against Toxoplasma gondii. 2005 Int. J. Antimicrob. Agents pmid:15664482
Nikkilä K et al. Serum and hepatic cholestanol, squalene and noncholesterol sterols in man: a study on liver transplantation. 1992 Hepatology pmid:1568728
Nikkilä K et al. Sterol parameters as markers of liver function in primary biliary cirrhosis before and after liver transplantation. 2005 Transpl. Int. pmid:15691276
Clarenbach JJ et al. Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. 2005 Metab. Clin. Exp. pmid:15736111
Readman JW et al. The use of steroid markers to assess sewage contamination of the Black Sea. 2005 Mar. Pollut. Bull. pmid:15757694
Corradini SG et al. Comparison of changes in lipid profile after bilio-intestinal bypass and gastric banding in patients with morbid obesity. 2005 Obes Surg pmid:15826472
Cardona ME et al. Biochemical intestinal parameters in germ-free minipigs and rats and in ex-germ-free minipigs and rats monoassociated with Escherichia coli. 2005 J Vet Med A Physiol Pathol Clin Med pmid:15836440
Clemen CS et al. Cerebrotendinous xanthomatosis: a treatable ataxia. 2005 Neurology pmid:15851751
Gagné F et al. Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes. 2006 Ecotoxicol. Environ. Saf. pmid:15923035
Miettinen TA et al. Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endarterectomy. 2005 J. Am. Coll. Cardiol. pmid:15936608
Beattie ME et al. Sterol structure determines miscibility versus melting transitions in lipid vesicles. 2005 Biophys. J. pmid:15951379
Rugonyi S et al. Kinetics for the collapse of trilayer liquid-crystalline disks from a monolayer at an air-water interface. 2005 Langmuir pmid:16042458
Peng X et al. Tracing anthropogenic contamination in the Pearl River estuarine and marine environment of South China Sea using sterols and other organic molecular markers. 2005 Mar. Pollut. Bull. pmid:16115503
Hoenig MR et al. Cholestanol: a serum marker to guide LDL cholesterol-lowering therapy. 2006 Atherosclerosis pmid:16216250
Apel-Paz M et al. Impact of membrane cholesterol content on the resistance of vesicles to surfactant attack. 2005 Langmuir pmid:16229500