Coprosterol

Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.

Cross Reference

Introduction

To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprosterol?

Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coprosterol

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cataract D002386 34 associated lipids
Alcoholism D000437 27 associated lipids
Xanthomatosis D014973 17 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Biliary Fistula D001658 13 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Total 9

PubChem Associated disorders and diseases

What pathways are associated with Coprosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Coprosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprosterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Coprosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprosterol?

Rodent Model

Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Coprosterol

Download all related citations
Per page 10 20 50 100 | Total 485
Authors Title Published Journal PubMed Link
Alhariri A et al. Clinical report: A patient with a late diagnosis of cerebrotendinous xanthomatosis and a response to treatment. 2017 Am. J. Med. Genet. A pmid:28590052
Chen C et al. Clinical and molecular genetic features of cerebrotendinous xanthomatosis patients in Chinese families. 2017 Metab Brain Dis pmid:28623566
Othman RA et al. Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe. 2017 J. Pediatr. pmid:28625503
Lamiquiz-Moneo I et al. ABCG5/G8 gene is associated with hypercholesterolemias without mutation in candidate genes and noncholesterol sterols. J Clin Lipidol pmid:29066094
Tibrewal S et al. Cerebrotendinous xanthomatosis: early diagnosis on the basis of juvenile cataracts. 2017 J AAPOS pmid:29079218
Cabral AC et al. An integrated evaluation of some faecal indicator bacteria (FIB) and chemical markers as potential tools for monitoring sewage contamination in subtropical estuaries. 2018 Environ. Pollut. pmid:29339343
Katz DA et al. Peripheral neuropathy in cerebrotendinous xanthomatosis. 1985 Arch. Neurol. pmid:2994606
Miettinen TA et al. Cholesterol precursor sterols, plant sterols, and cholestanol in human bile and gallstones. 1986 Gastroenterology pmid:3081398
Hayashi E et al. Fecal bile acids and neutral sterols in rats with spontaneous colon cancer. 1986 Int. J. Cancer pmid:3082773
Midtvedt T et al. Influence of peroral antibiotics upon the biotransformatory activity of the intestinal microflora in healthy subjects. 1986 Eur. J. Clin. Invest. pmid:3084266
Kasama T and Seyama Y Biochemical diagnosis of cerebrotendinous xanthomatosis using reversed phase thin layer chromatography. 1986 J. Biochem. pmid:3086296
Clifford AJ et al. Effects of dietary triglycerides on serum and liver lipids and sterol excretion of rats. 1986 J. Nutr. pmid:3088226
Bhattacharyya AK Differences in uptake and esterification of saturated analogues of cholesterol by rat small intestine. 1986 Am. J. Physiol. pmid:3094380
Parker F Normocholesterolemic xanthomatosis. 1986 Arch Dermatol pmid:3096220
Seidel SB et al. Minor and trace sterols from marine invertebrates 56. Novel coprostanols from the marine sponge Petrosia ficiformis. 1986 Steroids pmid:3101232
Lozano R et al. Metabolism of sterols of varying ring unsaturation and methylation by Caenorhabditis elegans. 1987 Lipids pmid:3104715
Salen G et al. Increased concentrations of cholestanol and apolipoprotein B in the cerebrospinal fluid of patients with cerebrotendinous xanthomatosis. Effect of chenodeoxycholic acid. 1987 N. Engl. J. Med. pmid:3106810
Peuchant E et al. Relationship between fecal neutral steroid concentrations and malignancy in colon cells. 1987 Cancer pmid:3111679
van Faassen A et al. Bile acids, neutral steroids, and bacteria in feces as affected by a mixed, a lacto-ovovegetarian, and a vegan diet. 1987 Am. J. Clin. Nutr. pmid:3120571
Midtvedt T et al. Establishment of a biochemically active intestinal ecosystem in ex-germfree rats. 1987 Appl. Environ. Microbiol. pmid:3124742
Garraffo HM and Gros EG Biosynthesis of bufadienolides in toads. VI. Experiments with [1,2-3H]cholesterol, [21-14C]coprostanol, and 5 beta-[21-14 C]pregnanolone in the toad Bufo arenarum. 1986 Sep-Oct Steroids pmid:3127947
Hirsch D et al. DSC, X-ray and NMR properties of cholesterol-cholestanol-dihydrate crystals. 1988 Clin. Chim. Acta pmid:3133139
Koivisto PV and Miettinen TA Plasma and biliary cholestanol related to steroid metabolism in familial hypercholesterolemia patients with and without ileal exclusion. 1988 Clin. Chim. Acta pmid:3133140
Midtvedt AC et al. Development of five metabolic activities associated with the intestinal microflora of healthy infants. 1988 Jul-Aug J. Pediatr. Gastroenterol. Nutr. pmid:3135382
Shefer S et al. Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase. 1988 J. Clin. Invest. pmid:3143743
Elliott CG and Sansome E The influence of sterols on meiosis in Phytophthora cactorum. 1977 J. Gen. Microbiol. pmid:319196
Kay RM and Truswell AS Effect of citrus pectin on blood lipids and fecal steroid excretion in man. 1977 Am. J. Clin. Nutr. pmid:319647
Gustafsson BE and Norin KE Development of germfree animal characteristics in conventional rats in antibiotics. 1977 Acta Pathol Microbiol Scand B pmid:320818
Reddy BS et al. Fecal bile acids and cholesterol metabolites of patients with ulcerative colitis, a high-risk group for development of colon cancer. 1977 Cancer Res. pmid:322859
Nigro ND et al. A comparison of the effects of the hypocholesteremic agents, cholestyramine and candicidin, on the induction of intestinal tumors in rats by azoxymethane. 1977 Cancer Res. pmid:328141
Sadzikowski MR et al. Cholesterol-reducing bacterium from human feces. 1977 Appl. Environ. Microbiol. pmid:335969
Sulpice JC et al. Diet and sterol biohydrogenation in the rat: occurrence of epicoprostanol. 1978 Lipids pmid:345032
Huang CT et al. Fecal steroids in diarrhea. II. Travellers' diarrhea. 1978 Am. J. Clin. Nutr. pmid:345794
Lee SP Enhanced fluid transport across gallbladder mucosa in experimental cholelithiasis. 1978 Am. J. Physiol. pmid:352156
Férézou J et al. Daily elimination of fecal neutral sterols by humans. 1978 Digestion pmid:367852
Gallo-Torres HE et al. Some effects of deoxycholate administration on the metabolism of cholesterol in man. 1979 Am. J. Clin. Nutr. pmid:377936
Lee SP and Scott AJ Dihydrocholesterol-induced gallstones in the rabbit: evidence that bile acids cause gallbladder epithelial injury. 1979 Br J Exp Pathol pmid:383127
Smith LB et al. The effect of dietary corn oil and cholesterol level on the neutral steroid composition in the large intestinal contents of the rat. 1979 J. Nutr. pmid:385812
Skrede S et al. Biosynthesis of cholestanol from bile acid intermediates in the rabbit and the rat. 1985 J. Biol. Chem. pmid:3917436
Skrede S et al. A novel pathway for biosynthesis of cholestanol with 7 alpha-hydroxylated C27-steroids as intermediates, and its importance for the accumulation of cholestanol in cerebrotendinous xanthomatosis. 1985 J. Clin. Invest. pmid:3919058
Björkhem I et al. On the structural specificity in the regulation of the hydroxymethylglutaryl-CoA reductase and the cholesterol-7 alpha-hydroxylase in rats. Effects of cholestanol feeding. 1985 Biochim. Biophys. Acta pmid:3924107
Plank L et al. Effect of sterol incorporation on head group separation in liposomes. 1985 Chem. Phys. Lipids pmid:3924423
White SW Cerebrotendinous xanthomatosis is treatable. 1985 Pediatr Dermatol pmid:3925446
Salen G and Grundy SM The metabolism of cholestanol, cholesterol, and bile acids in cerebrotendinous xanthomatosis. 1973 J. Clin. Invest. pmid:4355999
Endo T et al. Bile acid metabolism in benign recurrent intrahepatic cholestasis. Comparative studies on the icteric and anicteric phases of a single case. 1979 Gastroenterology pmid:437403
Salen G and Polito A Biosynthesis of 5 -cholestan-3 -ol in cerebrotendinous xanthomatosis. 1972 J. Clin. Invest. pmid:4550120
Ghosh D and Tinoco J Monolayer interactions of individual lecithins with natural sterols. 1972 Biochim. Biophys. Acta pmid:4557356
Eyssen H et al. Role of the cecum in maintaing 5 -steroid- and fatty acid-reducing activity of the rat intestinal microflora. 1972 J. Nutr. pmid:4563003
Norman AW et al. Studies on the biological properties of polyene antibiotics: comparison of other polyenes with filipin in their ability to interact specifically with sterol. 1972 Biochim. Biophys. Acta pmid:4565643
Smith AG et al. The intermediacy of 3-oxo steroids in the conversion of cholest-5-en-3 -ol into 5 -cholestan-3 -ol by the starfish Asterias rubens and Porania pulvillus. 1972 Biochem. J. pmid:4566194