Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.
To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Coprosterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Brain Diseases, Metabolic | D001928 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Norlin M et al. | On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation. | 2003 | J. Lipid Res. | pmid:12777473 |
| Schief WR et al. | Liquid-crystalline collapse of pulmonary surfactant monolayers. | 2003 | Biophys. J. | pmid:12770885 |
| Puglisi E et al. | Cholesterol, beta-sitosterol, ergosterol, and coprostanol in agricultural soils. | 2003 Mar-Apr | J. Environ. Qual. | pmid:12708669 |
| Ottoson J and Stenström TA | Faecal contamination of greywater and associated microbial risks. | 2003 | Water Res. | pmid:12688699 |
| Bortolomeazzi R et al. | Presence of phytosterol oxides in crude vegetable oils and their fate during refining. | 2003 | J. Agric. Food Chem. | pmid:12670187 |
| Jaffé R et al. | Organic compounds and trace metals of anthropogenic origin in sediments from Montego Bay, Jamaica: assessment of sources and distribution pathways. | 2003 | Environ. Pollut. | pmid:12628208 |
| Nimmo MR and Cross NL | Structural features of sterols required to inhibit human sperm capacitation. | 2003 | Biol. Reprod. | pmid:12606419 |
| Wiegand V et al. | Transport of plasma membrane-derived cholesterol and the function of Niemann-Pick C1 Protein. | 2003 | FASEB J. | pmid:12594172 |
| Miettinen TA et al. | Serum noncholesterol sterols during inhibition of cholesterol synthesis by statins. | 2003 | J. Lab. Clin. Med. | pmid:12577049 |
| Addona GH et al. | Low chemical specificity of the nicotinic acetylcholine receptor sterol activation site. | 2003 | Biochim. Biophys. Acta | pmid:12543379 |