Coprosterol

Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.

Cross Reference

Introduction

To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprosterol?

Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coprosterol

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cataract D002386 34 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Alcoholism D000437 27 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Xanthomatosis D014973 17 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 9

PubChem Associated disorders and diseases

What pathways are associated with Coprosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coprosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprosterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Coprosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprosterol?

Rodent Model

Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Coprosterol

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Authors Title Published Journal PubMed Link
pmid:
Inoue K et al. Cholestanol induces apoptosis of cerebellar neuronal cells. 1999 Biochem. Biophys. Res. Commun. pmid:10066446
Fadden K et al. Steroid metabolism along the gastrointestinal tract of the cannulated pig. 1999 Eur. J. Cancer Prev. pmid:10091041
Gylling H et al. Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population. 1999 J. Lipid Res. pmid:10191283
Uchida K et al. Transformation of bile acids and sterols by clostridia (fusiform bacteria) in Wistar rats. 1999 Lipids pmid:10230721
Batta AK et al. Highly simplified method for gas-liquid chromatographic quantitation of bile acids and sterols in human stool. 1999 J. Lipid Res. pmid:10357847
Panda SK et al. Correlation of neomycin, faecal neutral and acid sterols with colon carcinogenesis in rats. 1999 Br. J. Cancer pmid:10376962
Radhakrishnan A and McConnell HM Condensed complexes of cholesterol and phospholipids. 1999 Biophys. J. pmid:10465761
Fernandes MB et al. Sedimentary 4-desmethyl sterols and n-alkanols in an eutrophic urban estuary, Capibaribe River, Brazil. 1999 Sci. Total Environ. pmid:10466230
Larking PW Cancer and low levels of plasma cholesterol: the relevance of cholesterol precursors and products to incidence of cancer. 1999 Prev Med pmid:10564630
Liendo A et al. Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes. 1999 Mol. Biochem. Parasitol. pmid:10589983
Radhakrishnan A and McConnell HM Electric field effect on cholesterol-phospholipid complexes. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10655486
Inoue K et al. Cholestanol induces apoptosis of corneal endothelial and lens epithelial cells. 2000 Invest. Ophthalmol. Vis. Sci. pmid:10752932
Verrips A et al. Presence of diarrhea and absence of tendon xanthomas in patients with cerebrotendinous xanthomatosis. 2000 Arch. Neurol. pmid:10768627
Miettinen TA et al. Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: relation to basal serum cholestanol. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10807752
Collinder E et al. Six intestinal microflora-associated characteristics in sport horses. 2000 Equine Vet. J. pmid:10836477
Björkhem I and Leitersdorf E Sterol 27-hydroxylase deficiency: a rare cause of xanthomas in normocholesterolemic humans. 2000 Trends Endocrinol. Metab. pmid:10856919
Friedman M et al. Lowering of plasma LDL cholesterol in hamsters by the tomato glycoalkaloid tomatine. 2000 Food Chem. Toxicol. pmid:10942315
Collinder E et al. Influence of bacitracin on microbial functions in the gastrointestinal tract of horses. 2000 Equine Vet. J. pmid:10952385
Fleck JD et al. Neuroimages: cerebrotendinous xanthomatosis. 2000 Neurology pmid:10953208