Coprosterol

Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.

Cross Reference

Introduction

To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprosterol?

Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coprosterol

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cataract D002386 34 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Alcoholism D000437 27 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Xanthomatosis D014973 17 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 9

PubChem Associated disorders and diseases

What pathways are associated with Coprosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coprosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprosterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Coprosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprosterol?

Rodent Model

Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Coprosterol

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Authors Title Published Journal PubMed Link
Mutanen A et al. Serum plant sterols, cholestanol, and cholesterol precursors associate with histological liver injury in pediatric onset intestinal failure. 2014 Am. J. Clin. Nutr. pmid:25099547
Mignarri A et al. A suspicion index for early diagnosis and treatment of cerebrotendinous xanthomatosis. 2014 J. Inherit. Metab. Dis. pmid:24442603
Yoshinaga T et al. Clinical and radiological findings of a cerebrotendinous xanthomatosis patient with a novel p.A335V mutation in the CYP27A1 gene. 2014 Intern. Med. pmid:25447658
Sistiaga A et al. The Neanderthal meal: a new perspective using faecal biomarkers. 2014 PLoS ONE pmid:24963925
Hallikainen M et al. Cholesterol metabolism and serum non-cholesterol sterols: summary of 13 plant stanol ester interventions. 2014 Lipids Health Dis pmid:24766766
Imperatore C et al. Phallusiasterols A and B: two new sulfated sterols from the Mediterranean tunicate Phallusia fumigata and their effects as modulators of the PXR receptor. 2014 Mar Drugs pmid:24705503
Mandrile G et al. Cerebrotendinous xanthomatosis: recurrence of the CYP27A1 mutation p.Arg479Cys in Sardinia. 2014 Neurol. Sci. pmid:24584636
von der Lühe B et al. Investigation of sterols as potential biomarkers for the detection of pig (S. s. domesticus) decomposition fluid in soils. 2013 Forensic Sci. Int. pmid:23583120
Björkhem I Cerebrotendinous xanthomatosis. 2013 Curr. Opin. Lipidol. pmid:23759795
de Medina P et al. Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A. 2013 Biochimie pmid:22709869
Ginanneschi F et al. Polyneuropathy in cerebrotendinous xanthomatosis and response to treatment with chenodeoxycholic acid. 2013 J. Neurol. pmid:22878431
Martini G et al. Long-term bone density evaluation in cerebrotendinous xanthomatosis: evidence of improvement after chenodeoxycholic acid treatment. 2013 Calcif. Tissue Int. pmid:23212544
Furtula V et al. Inorganic nitrogen, sterols and bacterial source tracking as tools to characterize water quality and possible contamination sources in surface water. 2012 Water Res. pmid:22197263
Hope BK et al. A state-wide survey in Oregon (USA) of trace metals and organic chemicals in municipal effluent. 2012 Sci. Total Environ. pmid:22244355
Kaczocha M et al. Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. 2012 ACS Chem Neurosci pmid:22860204
Souza DS et al. Evaluation of tropical water sources and mollusks in southern Brazil using microbiological, biochemical, and chemical parameters. 2012 Ecotoxicol. Environ. Saf. pmid:22036209
Lahti M and Oikari A Vertical distribution of pharmaceuticals in lake sediments-citalopram as potential chemomarker. 2012 Environ. Toxicol. Chem. pmid:22639393
Pande S et al. Antihypercholesterolaemic influence of dietary tender cluster beans (Cyamopsis tetragonoloba) in cholesterol fed rats. 2012 Indian J. Med. Res. pmid:22561629
Kumar M et al. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. 2012 Exp Diabetes Res pmid:22611376
Martins CC et al. Multi-molecular markers and metals as tracers of organic matter inputs and contamination status from an Environmental Protection Area in the SW Atlantic (Laranjeiras Bay, Brazil). 2012 Sci. Total Environ. pmid:22244354