Coprosterol

Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.

Cross Reference

Introduction

To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coprosterol?

Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coprosterol

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cataract D002386 34 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Alcoholism D000437 27 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Xanthomatosis D014973 17 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 9

PubChem Associated disorders and diseases

What pathways are associated with Coprosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coprosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coprosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coprosterol?

Related references are published most in these journals:

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What genes are associated with Coprosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coprosterol?

Rodent Model

Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Coprosterol

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Authors Title Published Journal PubMed Link
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Midtvedt AC and Midtvedt T Conversion of cholesterol to coprostanol by the intestinal microflora during the first two years of human life. 1993 J. Pediatr. Gastroenterol. Nutr. pmid:8229543
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Urbina JA et al. Antiproliferative effects of delta 24(25) sterol methyl transferase inhibitors on Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies. 1996 Jul-Aug Chemotherapy pmid:8804798
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Morita T et al. Cholesterol-lowering effects of soybean, potato and rice proteins depend on their low methionine contents in rats fed a cholesterol-free purified diet. 1997 J. Nutr. pmid:9082032
Adachi J et al. Epicoprostanol found in adipocere from five human autopsies. 1997 Lipids pmid:9397400
Hagen JP and McConnell HM Liquid-liquid immiscibility in lipid monolayers. 1997 Biochim. Biophys. Acta pmid:9370239
Urbina JA et al. Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii. 1997 Antimicrob. Agents Chemother. pmid:9210660
Gerasimov OV et al. Acid-catalyzed plasmenylcholine hydrolysis and its effect on bilayer permeability: a quantitative study. 1997 Biochim. Biophys. Acta pmid:9092707
Gylling H et al. Oral guar gum treatment of intrahepatic cholestasis and pruritus in pregnant women: effects on serum cholestanol and other non-cholesterol sterols. 1998 Eur. J. Clin. Invest. pmid:9650008
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Srikumar TS et al. Analysis of fecal bile acids and neutral steroids using gas-liquid chromatography. 1998 Ann. Nutr. Metab. pmid:9745109
Miettinen TA et al. Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study. Finnish 4S Investigators. 1998 BMJ pmid:9552949
Wallis EJ et al. Cholestanol and survival with simvastatin. More data are needed. 1998 BMJ pmid:9794879
Reddy S et al. Faecal pH, bile acid and sterol concentrations in premenopausal Indian and white vegetarians compared with white omnivores. 1998 Br. J. Nutr. pmid:9771336
Fernandes MB et al. Sedimentary 4-desmethyl sterols and n-alkanols in an eutrophic urban estuary, Capibaribe River, Brazil. 1999 Sci. Total Environ. pmid:10466230
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Batta AK et al. Highly simplified method for gas-liquid chromatographic quantitation of bile acids and sterols in human stool. 1999 J. Lipid Res. pmid:10357847
Gylling H et al. Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population. 1999 J. Lipid Res. pmid:10191283
Uchida K et al. Transformation of bile acids and sterols by clostridia (fusiform bacteria) in Wistar rats. 1999 Lipids pmid:10230721
Inoue K et al. Cholestanol induces apoptosis of cerebellar neuronal cells. 1999 Biochem. Biophys. Res. Commun. pmid:10066446