| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
Total
1
22(r)-hydroxycholesterol
22(r)-hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22(r)-hydroxycholesterol is associated with abnormalities such as Transient Ischemic Attack, Still, Neurodegenerative Disorders and Senile Plaques. The involved functions are known as Binding (Molecular Function), inhibitors, mRNA Expression, Gene Expression and Transcription, Genetic. 22(r)-hydroxycholesterol often locates in Blood, Protoplasm, Extracellular, Cytosol and Cytoplasm. The associated genes with 22(r)-hydroxycholesterol are CCL2 gene, IL8RB gene, CALCA gene and GRM5 gene. The related lipids are 22-hydroxycholesterol, Lipopolysaccharides, 15-deoxyprostaglandin J2 and 7-ketocholesterol.
Cross Reference
Introduction
To understand associated biological information of 22(r)-hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 22(r)-hydroxycholesterol?
22(r)-hydroxycholesterol is suspected in Neurodegenerative Disorders, Transient Ischemic Attack, Senile Plaques and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 22(r)-hydroxycholesterol
PubChem Associated disorders and diseases
What pathways are associated with 22(r)-hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 22(r)-hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 22(r)-hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 22(r)-hydroxycholesterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 22(r)-hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 22(r)-hydroxycholesterol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 22(r)-hydroxycholesterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Verhagen JC et al. | Physical effects of biologically formed cholesterol oxidation products on lipid membranes investigated with fluorescence depolarization spectroscopy and electron spin resonance. | 1996 | J. Lipid Res. | pmid:8827521 |
| Mele PG et al. | Site of action of proteinases in the activation of steroidogenesis in rat adrenal gland. | 1996 | Biochim. Biophys. Acta | pmid:8599603 |
| Sugano S et al. | Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: accumulation of the intermediate modulated by the adrenodoxin level. | 1996 | J. Biochem. | pmid:8947841 |
| Janowski BA et al. | An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. | 1996 | Nature | pmid:8878485 |
| Picard-Hagen N et al. | Glucocorticoids enhance the cholesterol side-chain cleavage activity of ovine adrenocortical mitochondria. | 1995 | J. Steroid Biochem. Mol. Biol. | pmid:7577721 |
| Brannian JD et al. | Hydrogen peroxide suppresses low-density lipoprotein (LDL) uptake and LDL-supported steroidogenesis by porcine luteal cells. | 1995 | Mol. Cell. Endocrinol. | pmid:7556884 |
| Musicki B et al. | Inhibition of protein synthesis and hormone-sensitive steroidogenesis in response to hydrogen peroxide in rat luteal cells. | 1994 | Endocrinology | pmid:7507829 |
| Khanna A et al. | Heat shock protein induction blocks hormone-sensitive steroidogenesis in rat luteal cells. | 1994 | Steroids | pmid:8140601 |
| Abayasekara DR et al. | Mode of action of prostaglandin F2 alpha in human luteinized granulosa cells: role of protein kinase C. | 1993 | Mol. Cell. Endocrinol. | pmid:8143907 |
| Stocco DM et al. | The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells. | 1993 | Endocrinology | pmid:8243310 |