Björkhem I |
Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. |
2006 |
J. Intern. Med. |
pmid:17116000
|
Klass DM et al. |
Biliary lipids, cholesterol and bile synthesis: different adaptive mechanisms to dietary cholesterol in lean and obese subjects. |
2006 |
Aliment. Pharmacol. Ther. |
pmid:16573792
|
Kummerow FA et al. |
27-Hydroxycholesterol causes remodeling in endothelial cell membrane lipid composition comparable to remodeling in the failed vein grafts of CABG patients. |
2006 |
Life Sci. |
pmid:16154158
|
Chen W et al. |
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. |
2007 |
Cell Metab. |
pmid:17189208
|
Meaney S et al. |
Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid. |
2007 |
J. Lipid Res. |
pmid:17251592
|
Li T et al. |
PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine. |
2007 |
J. Lipid Res. |
pmid:17088262
|
Teunissen CE et al. |
24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis. |
2007 |
J. Neurosci. Res. |
pmid:17410599
|
Hansson M et al. |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
2007 |
J. Intern. Med. |
pmid:17444890
|
Burkard I et al. |
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. |
2007 |
Atherosclerosis |
pmid:17107679
|
Luomala M et al. |
Osteopontin levels are associated with cholesterol synthesis markers in mildly hypercholesterolaemic patients. |
2007 |
Acta Cardiol |
pmid:17536607
|
Crosignani A et al. |
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease. |
2007 |
Clin. Chim. Acta |
pmid:17482152
|
Li X et al. |
Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes. |
2007 |
J. Lipid Res. |
pmid:17890683
|
Umetani M et al. |
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. |
2007 |
Nat. Med. |
pmid:17873880
|
de Vogel-van den Bosch HM et al. |
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:18356535
|
Weiner MF et al. |
Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury. |
2008 |
Brain Inj |
pmid:18568715
|
Ghribi O |
Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle. |
2008 |
J. Alzheimers Dis. |
pmid:19096164
|
Cheng D et al. |
Regulation of alpha-synuclein expression by liver X receptor ligands in vitro. |
2008 |
Neuroreport |
pmid:18841091
|
Lange Y et al. |
Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. |
2008 |
J. Biol. Chem. |
pmid:18024962
|
Zhang JR et al. |
Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking. |
2008 |
J. Clin. Invest. |
pmid:18483620
|
DuSell CD et al. |
27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. |
2008 |
Mol. Endocrinol. |
pmid:17872378
|
Crosignani A et al. |
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis. |
2008 |
Clin. Chim. Acta |
pmid:18538136
|
Rantham Prabhakara JP et al. |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. |
2008 |
J. Neurochem. |
pmid:19014385
|
Sharma S et al. |
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. |
2008 |
Neurobiol. Dis. |
pmid:18775495
|
DuSell CD and McDonnell DP |
27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling. |
2008 |
Trends Pharmacol. Sci. |
pmid:18722677
|
Riendeau V and Garenc C |
Effect of 27-hydroxycholesterol on survival and death of human macrophages and vascular smooth muscle cells. |
2009 |
Free Radic. Res. |
pmid:19672739
|
Karuna R et al. |
Dopant assisted-atmospheric pressure photoionization (DA-APPI) liquid chromatography-mass spectrometry for the quantification of 27-hydroxycholesterol in plasma. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:19121981
|
Escher G et al. |
Role of CYP27A1 in progesterone metabolism in vitro and in vivo. |
2009 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:19671838
|
Olkkonen VM and Hynynen R |
Interactions of oxysterols with membranes and proteins. |
2009 |
Mol. Aspects Med. |
pmid:19248802
|
Gilardi F et al. |
Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling. |
2009 |
Neuroscience |
pmid:19665519
|
Mateos L et al. |
Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro. |
2009 |
Brain Pathol. |
pmid:18503570
|
Prasanthi JR et al. |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. |
2009 |
Mol Neurodegener |
pmid:19126211
|
Koschack J et al. |
Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals. |
2009 |
Neurobiol. Aging |
pmid:18061309
|
Lange Y et al. |
Regulation of fibroblast mitochondrial 27-hydroxycholesterol production by active plasma membrane cholesterol. |
2009 |
J. Lipid Res. |
pmid:19401598
|
van den Kommer TN et al. |
Total cholesterol and oxysterols: early markers for cognitive decline in elderly? |
2009 |
Neurobiol. Aging |
pmid:17888546
|
Solomon A et al. |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. |
2009 |
Neurosci. Lett. |
pmid:19560513
|
Honda A et al. |
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. |
2009 |
J. Lipid Res. |
pmid:18815436
|
Kim WS et al. |
Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons. |
2009 |
J. Alzheimers Dis. |
pmid:19158428
|
Morello F et al. |
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. |
2009 |
Atherosclerosis |
pmid:19426978
|
Blom T et al. |
FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages. |
2010 |
Circ. Res. |
pmid:20056921
|
Dasari B et al. |
The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells. |
2010 |
BMC Ophthalmol |
pmid:20836858
|
Iuliano L et al. |
Vitamin E and enzymatic/oxidative stress-driven oxysterols in amnestic mild cognitive impairment subtypes and Alzheimer's disease. |
2010 |
J. Alzheimers Dis. |
pmid:21504117
|
Crow JA et al. |
Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids. |
2010 |
Biochim. Biophys. Acta |
pmid:19761868
|
DuSell CD et al. |
The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. |
2010 |
Endocrinology |
pmid:20501668
|
Marwarha G et al. |
Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. |
2010 |
J. Alzheimers Dis. |
pmid:20157255
|
Taylor JM et al. |
Overexpression of steroidogenic acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI. |
2010 |
Cardiovasc. Res. |
pmid:20083572
|
Weingärtner O et al. |
An alternative pathway of reverse cholesterol transport: the oxysterol 27-hydroxycholesterol. |
2010 |
Atherosclerosis |
pmid:19801147
|
Schüle R et al. |
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis. |
2010 |
J. Lipid Res. |
pmid:19812052
|
Karuna R et al. |
Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism. |
2011 |
Atherosclerosis |
pmid:21130455
|
Mateos L et al. |
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease. |
2011 |
J. Alzheimers Dis. |
pmid:21297254
|
Torres CG et al. |
27-hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype. |
2011 |
Oncol. Rep. |
pmid:21567091
|