20-hydroxyecdysone

20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.

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Introduction

To understand associated biological information of 20-hydroxyecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 20-hydroxyecdysone?

20-hydroxyecdysone is suspected in Congenital Abnormality, Obesity, Diabetes, Varicosity, Gilbert Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 20-hydroxyecdysone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 20-hydroxyecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 20-hydroxyecdysone?

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Location Cross reference Weighted score Related literatures
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What functions are associated with 20-hydroxyecdysone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 20-hydroxyecdysone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 20-hydroxyecdysone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 20-hydroxyecdysone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 20-hydroxyecdysone

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Authors Title Published Journal PubMed Link
Suang S et al. Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. 2017 PLoS ONE pmid:28369111
Mhashilkar AS et al. Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. 2016 PLoS Negl Trop Dis pmid:27300294
Childs LM et al. Disrupting Mosquito Reproduction and Parasite Development for Malaria Control. 2016 PLoS Pathog. pmid:27977810
Liu Y et al. The Sublethal Effects of β-Ecdysterone, a Highly Active Compound from Achyranthes bidentata Blume, on Grape Phylloxera, Daktulosphaira vitifoliae Fitch. 2016 PLoS ONE pmid:27824901
Thorat L et al. Desiccation stress induces developmental heterochrony in Drosophila melanogaster. 2016 J. Biosci. pmid:27581925
Wang D et al. The Steroid Hormone 20-Hydroxyecdysone Promotes the Cytoplasmic Localization of Yorkie to Suppress Cell Proliferation and Induce Apoptosis. 2016 J. Biol. Chem. pmid:27551043
Gokhale RH et al. Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling. 2016 Dev. Biol. pmid:27452628
Li K et al. 20-Hydroxyecdysone (20E) Primary Response Gene E75 Isoforms Mediate Steroidogenesis Autoregulation and Regulate Developmental Timing in Bombyx. 2016 J. Biol. Chem. pmid:27365399
Chiang YN et al. Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. 2016 PLoS Genet. pmid:27333054
Akagi K et al. A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster. 2016 Development pmid:27226323