20-hydroxyecdysone

20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.

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Introduction

To understand associated biological information of 20-hydroxyecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 20-hydroxyecdysone?

20-hydroxyecdysone is suspected in Congenital Abnormality, Obesity, Diabetes, Varicosity, Gilbert Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 20-hydroxyecdysone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 20-hydroxyecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 20-hydroxyecdysone?

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Location Cross reference Weighted score Related literatures
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What functions are associated with 20-hydroxyecdysone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 20-hydroxyecdysone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 20-hydroxyecdysone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 20-hydroxyecdysone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 20-hydroxyecdysone

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Authors Title Published Journal PubMed Link
Eichner C et al. Characterization of a novel RXR receptor in the salmon louse (Lepeophtheirus salmonis, Copepoda) regulating growth and female reproduction. 2015 BMC Genomics pmid:25765704
Cai MJ et al. G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane. 2014 Cell Commun. Signal pmid:24507557
Liu W et al. In a nongenomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription. 2014 Endocrinology pmid:24517229
Liu W et al. Phospholipase Cγ1 connects the cell membrane pathway to the nuclear receptor pathway in insect steroid hormone signaling. 2014 J. Biol. Chem. pmid:24692553
Ono H Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile hormone in Drosophila melanogaster. 2014 Dev. Biol. pmid:24727669
Niitsu S et al. Ecdysteroid-induced programmed cell death is essential for sex-specific wing degeneration of the wingless-female winter moth. 2014 PLoS ONE pmid:24558499
Li Y et al. Steroid signaling promotes stem cell maintenance in the Drosophila testis. 2014 Dev. Biol. pmid:25093968
Gabrieli P et al. Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25368171
Li Z et al. CYP18A1 regulates tissue-specific steroid hormone inactivation in Bombyx mori. 2014 Insect Biochem. Mol. Biol. pmid:25173591
Zhao B et al. Regulation of the gut-specific carboxypeptidase: a study using the binary Gal4/UAS system in the mosquito Aedes aegypti. 2014 Insect Biochem. Mol. Biol. pmid:25152428