22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Graf GA et al. | ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. | 2003 | J. Biol. Chem. | pmid:14504269 |
| KALLIANOS AG et al. | Identification of the D-glucosides of stigmasterol, sitosterol and campesterol in tobacco and cigarette smoke. | 1963 | Biochem. J. | pmid:14030353 |
| Mezine I et al. | Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy. | 2003 | J. Agric. Food Chem. | pmid:12952413 |
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| Ntanios FY et al. | Effects of various amounts of dietary plant sterol esters on plasma and hepatic sterol concentration and aortic foam cell formation of cholesterol-fed hamsters. | 2003 | Atherosclerosis | pmid:12860249 |
| Watts GF et al. | Effect of a statin on hepatic apolipoprotein B-100 secretion and plasma campesterol levels in the metabolic syndrome. | 2003 | Int. J. Obes. Relat. Metab. Disord. | pmid:12821974 |
| Hendriks HF et al. | Safety of long-term consumption of plant sterol esters-enriched spread. | 2003 | Eur J Clin Nutr | pmid:12771969 |
| Gorinstein S et al. | Comparison of the contents of the main biochemical compounds and the antioxidant activity of some Spanish olive oils as determined by four different radical scavenging tests. | 2003 | J. Nutr. Biochem. | pmid:12742543 |
| Chan DC et al. | Plasma markers of cholesterol homeostasis and apolipoprotein B-100 kinetics in the metabolic syndrome. | 2003 | Obes. Res. | pmid:12690090 |
| Schaller H | The role of sterols in plant growth and development. | 2003 | Prog. Lipid Res. | pmid:12689617 |
| Awad AB et al. | Effect of phytosterols on cholesterol metabolism and MAP kinase in MDA-MB-231 human breast cancer cells. | 2003 | J. Nutr. Biochem. | pmid:12667603 |