22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nguyen HT et al. | Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. | 2013 | Plant Physiol. Biochem. | pmid:24036394 |
| Jakulj L et al. | Plasma plant sterols serve as poor markers of cholesterol absorption in man. | 2013 | J. Lipid Res. | pmid:23178226 |
| O'Callaghan Y et al. | Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells. | 2013 | Biochimie | pmid:22561884 |
| Renner O et al. | Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease. | 2013 | BMC Gastroenterol | pmid:23406058 |
| Dai FJ et al. | Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters. | 2013 | Food Chem. Toxicol. | pmid:23287313 |
| Nasu K et al. | Impact of cholesterol metabolism on coronary plaque vulnerability of target vessels: a combined analysis of virtual histology intravascular ultrasound and optical coherence tomography. | 2013 | JACC Cardiovasc Interv | pmid:23769651 |
| Ras RT et al. | Consumption of plant sterol-enriched foods and effects on plasma plant sterol concentrations--a meta-analysis of randomized controlled studies. | 2013 | Atherosclerosis | pmid:24075766 |
| Martins CM et al. | Common sources and composition of phytosterols and their estimated intake by the population in the city of São Paulo, Brazil. | 2013 | Nutrition | pmid:23422542 |
| Barbosa SP et al. | Effects of ezetimibe on markers of synthesis and absorption of cholesterol in high-risk patients with elevated C-reactive protein. | 2013 | Life Sci. | pmid:23507424 |
| Lubinus T et al. | Fate of dietary phytosteryl/-stanyl esters: analysis of individual intact esters in human feces. | 2013 | Eur J Nutr | pmid:22777107 |
| Mo S et al. | Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry. | 2013 | Lipids | pmid:23884629 |
| Lupattelli G et al. | A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemias. | 2013 Mar-Apr | J Clin Lipidol | pmid:23415434 |
| Sawai S et al. | Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato. | 2014 | Plant Cell | pmid:25217510 |
| Salinas R et al. | Production of the anti-inflammatory compound 6-O-palmitoyl-3-O-β-D-glucopyranosylcampesterol by Callus cultures of Lopezia racemosa Cav. (Onagraceae). | 2014 | Molecules | pmid:24962399 |
| Radice M et al. | Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils. | 2014 | J Oleo Sci | pmid:25391685 |
| Ramprasath VR et al. | Consumption of a dietary portfolio of cholesterol lowering foods improves blood lipids without affecting concentrations of fat soluble compounds. | 2014 | Nutr J | pmid:25326876 |
| van der Made SM et al. | Consuming a buttermilk drink containing lutein-enriched egg yolk daily for 1 year increased plasma lutein but did not affect serum lipid or lipoprotein concentrations in adults with early signs of age-related macular degeneration. | 2014 | J. Nutr. | pmid:24991045 |
| Schött HF et al. | The relationships of phytosterols and oxyphytosterols in plasma and aortic valve cusps in patients with severe aortic stenosis. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24631689 |
| Tse TJ et al. | Reconstructing long-term trends in municipal sewage discharge into a small lake in northern Manitoba, Canada. | 2014 | Chemosphere | pmid:24405965 |
| Leyes P et al. | Effects of ezetimibe on cholesterol metabolism in HIV-infected patients with protease inhibitor-associated dyslipidemia: a single-arm intervention trial. | 2014 | BMC Infect. Dis. | pmid:25209653 |