22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yunker RL et al. | Simultaneous quantitation of biliary cholesterol, bile acids, and phospholipids (as fatty acids), by gas-liquid chromatography, with campesterol as internal standard. | 1981 | Clin. Chem. | pmid:7285335 |
| Wang C et al. | A unique patient with coexisting cerebrotendinous xanthomatosis and beta-sitosterolemia. | 1981 | Am. J. Med. | pmid:7258222 |
| Nes WR et al. | Steric effects at C-20 and C-24 on the metabolism of sterols by Tetrahymena pyriformis. | 1981 | J. Lipid Res. | pmid:6793681 |
| Bhattacharyya AK and Eggen DA | Effects of feeding cholesterol and mixed plant sterols on the fecal excretion of acidic steroids in rhesus monkeys. | 1984 | Atherosclerosis | pmid:6529445 |
| Dayal B et al. | Identification of 5 alpha-stanols in patients with sitosterolemia and xanthomatosis: stereochemistry of the protonolysis of steroidal organoboranes. | 1982 | Steroids | pmid:6297129 |
| Jwanny EW and Rashad MM | Metabolism of methanol by yeast and SCP production. | 1985 | J. Basic Microbiol. | pmid:4093874 |
| Salen G et al. | Increased plasma cholestanol and 5 alpha-saturated plant sterol derivatives in subjects with sitosterolemia and xanthomatosis. | 1985 | J. Lipid Res. | pmid:3989379 |
| Morrison AH and Ritter KS | Effect of host insect sterols on the development and sterol composition of Steinernema feltiae. | 1986 | Mol. Biochem. Parasitol. | pmid:3724794 |
| Bhattacharyya AK and Eggen DA | Effect of dietary cholesterol level on plasma campesterol concentration in rhesus monkeys. | 1987 | Ann. Nutr. Metab. | pmid:3662438 |
| Koivisto PV and Miettinen TA | Effect of ileal exclusion on plant sterol metabolism in familial hypercholesterolemia. | 1987 | Digestion | pmid:3443223 |
| Milhaud J et al. | Interaction of the polyene antibiotic filipin with model and natural membranes containing plant sterols. | 1988 | Biochim. Biophys. Acta | pmid:3401484 |
| Vuoristo M et al. | Serum plant sterols and lathosterol related to cholesterol absorption in coeliac disease. | 1988 | Clin. Chim. Acta | pmid:3383445 |
| Whitaker BD and Nelson DL | Sterol synergism in Paramecium tetraurelia. | 1988 | J. Gen. Microbiol. | pmid:3221193 |
| Bhattacharyya AK and Eggen DA | Studies on the mechanism of high intestinal absorption of cholesterol and campesterol in high-responding rhesus monkeys. | 1988 | Atherosclerosis | pmid:3214463 |
| pmid:29345907 | ||||
| Lin Y et al. | Oxidation of sitosterol and campesterol in foods upon cooking with liquid margarines without and with added plant sterol esters. | 2018 | Food Chem | pmid:28958544 |
| pmid:28911735 | ||||
| pmid:28812011 | ||||
| Ho XL and Loke WM | Dietary Plant Sterols Supplementation Increases In Vivo Nitrite and Nitrate Production in Healthy Adults: A Randomized, Controlled Study. | 2017 | J. Food Sci. | pmid:28708316 |
| pmid:28357621 |