22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lupattelli G et al. | Patterns of cholesterol metabolism: pathophysiological and therapeutic implications for dyslipidemias and the metabolic syndrome. | 2011 | Nutr Metab Cardiovasc Dis | pmid:21855307 |
| Labonté MÈ et al. | Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men. | 2011 | Mol Nutr Food Res | pmid:21656668 |
| Valitova JN et al. | Effects of sterol-binding agent nystatin on wheat roots: the changes in membrane permeability, sterols and glycoceramides. | 2011 | Phytochemistry | pmid:21726881 |
| Sabeva NS et al. | Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. | 2011 | J. Nutr. Biochem. | pmid:21111593 |
| de Araújo MF et al. | Simiranes A and B: erythroxylanes diterpenes and other compounds from Simira eliezeriana (Rubiaceae). | 2011 | Nat. Prod. Res. | pmid:21936665 |
| Niesor EJ et al. | Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects. | 2011 | Atherosclerosis | pmid:21982411 |
| Neil HA et al. | Impact of atorvastatin and omega-3 ethyl esters 90 on plasma plant sterol concentrations and cholesterol synthesis in type 2 diabetes: a randomised placebo controlled factorial trial. | 2010 | Atherosclerosis | pmid:21036355 |
| Silbernagel G et al. | The associations of cholesterol metabolism and plasma plant sterols with all-cause and cardiovascular mortality. | 2010 | J. Lipid Res. | pmid:20228406 |
| Jakulj L et al. | Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial. | 2010 | J. Lipid Res. | pmid:19828909 |
| Sharma M et al. | Inhibition of sterol biosynthesis reduces tombusvirus replication in yeast and plants. | 2010 | J. Virol. | pmid:20015981 |
| Hang J and Dussault P | A concise synthesis of beta-sitosterol and other phytosterols. | 2010 | Steroids | pmid:20685279 |
| van Himbergen TM et al. | Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19834104 |
| Okada K et al. | Lipid-lowering effects of ezetimibe for hypercholesterolemic patients with and without type 2 diabetes mellitus. | 2010 | Endocr. J. | pmid:20733267 |
| Miettinen TA et al. | Relation of non-cholesterol sterols to coronary risk factors and carotid intima-media thickness: the Cardiovascular Risk in Young Finns Study. | 2010 | Atherosclerosis | pmid:19963215 |
| Chung HY et al. | Simultaneous suppression of three genes related to brassinosteroid (BR) biosynthesis altered campesterol and BR contents, and led to a dwarf phenotype in Arabidopsis thaliana. | 2010 | Plant Cell Rep. | pmid:20169349 |
| Clément C et al. | Influence of colour type and previous cultivation on secondary metabolites in hypocotyls and leaves of maca (Lepidium meyenii Walpers). | 2010 | J. Sci. Food Agric. | pmid:20355123 |
| Rossard S et al. | Ergosterol triggers characteristic elicitation steps in Beta vulgaris leaf tissues. | 2010 | J. Exp. Bot. | pmid:20304987 |
| Hattori S and Hattori Y | Efficacy and safety of ezetimibe in patients undergoing hemodialysis. | 2010 | Endocr. J. | pmid:20885068 |
| Noto D et al. | Plasma non-cholesterol sterols: a useful diagnostic tool in pediatric hypercholesterolemia. | 2010 | Pediatr. Res. | pmid:20091938 |
| Forchielli ML et al. | The spectrum of plant and animal sterols in different oil-derived intravenous emulsions. | 2010 | Lipids | pmid:20049583 |