22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nguyen HT et al. | Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. | 2013 | Plant Physiol. Biochem. | pmid:24036394 |
| Dai FJ et al. | Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters. | 2013 | Food Chem. Toxicol. | pmid:23287313 |
| Martins CM et al. | Common sources and composition of phytosterols and their estimated intake by the population in the city of São Paulo, Brazil. | 2013 | Nutrition | pmid:23422542 |
| Vanmierlo T et al. | Dietary intake of plant sterols stably increases plant sterol levels in the murine brain. | 2012 | J. Lipid Res. | pmid:22279184 |
| Genser B et al. | Plant sterols and cardiovascular disease: a systematic review and meta-analysis. | 2012 | Eur. Heart J. | pmid:22334625 |
| Montserrat-de la Paz S et al. | The sterols isolated from Evening Primrose oil modulate the release of proinflammatory mediators. | 2012 | Phytomedicine | pmid:22819447 |
| Kurvinen A et al. | Parenteral plant sterols and intestinal failure-associated liver disease in neonates. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22197940 |
| Lupattelli G et al. | Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patients. | 2012 | Eur. J. Clin. Invest. | pmid:21793822 |
| Ito N et al. | An ultra performance liquid chromatographic method for determining phytosterol uptake by Caco-2 cells. | 2012 | Anal. Biochem. | pmid:22119071 |
| Lupattelli G et al. | Cholesterol metabolism differs after statin therapy according to the type of hyperlipemia. | 2012 | Life Sci. | pmid:22554491 |