22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Clouse SD | Arabidopsis mutants reveal multiple roles for sterols in plant development. | 2002 | Plant Cell | pmid:12215500 |
| Klahre U et al. | The Arabidopsis DIMINUTO/DWARF1 gene encodes a protein involved in steroid synthesis. | 1998 | Plant Cell | pmid:9761794 |
| Sawai S et al. | Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato. | 2014 | Plant Cell | pmid:25217510 |
| Fujioka S et al. | The Arabidopsis deetiolated2 mutant is blocked early in brassinosteroid biosynthesis. | 1997 | Plant Cell | pmid:9401120 |
| Choi JM et al. | Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities. | 2007 | Phytother Res | pmid:17604370 |
| Montserrat-de la Paz S et al. | The sterols isolated from Evening Primrose oil modulate the release of proinflammatory mediators. | 2012 | Phytomedicine | pmid:22819447 |
| Valitova JN et al. | Effects of sterol-binding agent nystatin on wheat roots: the changes in membrane permeability, sterols and glycoceramides. | 2011 | Phytochemistry | pmid:21726881 |
| Ijzerman RG et al. | The association between low birth weight and high levels of cholesterol is not due to an increased cholesterol synthesis or absorption: analysis in twins. | 2002 | Pediatr. Res. | pmid:12438663 |
| Noto D et al. | Plasma non-cholesterol sterols: a useful diagnostic tool in pediatric hypercholesterolemia. | 2010 | Pediatr. Res. | pmid:20091938 |
| Márk L and Paragh G | [Change in the cholesterol metabolism associated with the combined inhibition of synthesis and absorption]. | 2007 | Orv Hetil | pmid:17403635 |