22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Belayachi L et al. | Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in Jurkat cells. | 2014 | BMC Complement Altern Med | pmid:24460687 |
| Sawai S et al. | Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato. | 2014 | Plant Cell | pmid:25217510 |
| Salinas R et al. | Production of the anti-inflammatory compound 6-O-palmitoyl-3-O-β-D-glucopyranosylcampesterol by Callus cultures of Lopezia racemosa Cav. (Onagraceae). | 2014 | Molecules | pmid:24962399 |
| Benesch MG and McElhaney RN | A comparative calorimetric study of the effects of cholesterol and the plant sterols campesterol and brassicasterol on the thermotropic phase behavior of dipalmitoylphosphatidylcholine bilayer membranes. | 2014 | Biochim. Biophys. Acta | pmid:24704414 |
| Arfaoui MO et al. | Variation in oil content, fatty acid and phytosterols profile of Onopordum acanthium L. during seed development. | 2014 | Nat. Prod. Res. | pmid:25103576 |
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| Ramprasath VR et al. | Consumption of a dietary portfolio of cholesterol lowering foods improves blood lipids without affecting concentrations of fat soluble compounds. | 2014 | Nutr J | pmid:25326876 |
| van der Made SM et al. | Consuming a buttermilk drink containing lutein-enriched egg yolk daily for 1 year increased plasma lutein but did not affect serum lipid or lipoprotein concentrations in adults with early signs of age-related macular degeneration. | 2014 | J. Nutr. | pmid:24991045 |
| Hallikainen M et al. | Cholesterol metabolism and serum non-cholesterol sterols: summary of 13 plant stanol ester interventions. | 2014 | Lipids Health Dis | pmid:24766766 |
| Mansour MP et al. | Characterization of oilseed lipids from "DHA-producing Camelina sativa": a new transformed land plant containing long-chain omega-3 oils. | 2014 | Nutrients | pmid:24566436 |
| Schött HF et al. | The relationships of phytosterols and oxyphytosterols in plasma and aortic valve cusps in patients with severe aortic stenosis. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24631689 |
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| Leyes P et al. | Effects of ezetimibe on cholesterol metabolism in HIV-infected patients with protease inhibitor-associated dyslipidemia: a single-arm intervention trial. | 2014 | BMC Infect. Dis. | pmid:25209653 |
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| Nguyen HT et al. | Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. | 2013 | Plant Physiol. Biochem. | pmid:24036394 |
| Jakulj L et al. | Plasma plant sterols serve as poor markers of cholesterol absorption in man. | 2013 | J. Lipid Res. | pmid:23178226 |
| Renner O et al. | Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease. | 2013 | BMC Gastroenterol | pmid:23406058 |
| Nasu K et al. | Impact of cholesterol metabolism on coronary plaque vulnerability of target vessels: a combined analysis of virtual histology intravascular ultrasound and optical coherence tomography. | 2013 | JACC Cardiovasc Interv | pmid:23769651 |
| Ras RT et al. | Consumption of plant sterol-enriched foods and effects on plasma plant sterol concentrations--a meta-analysis of randomized controlled studies. | 2013 | Atherosclerosis | pmid:24075766 |
| Martins CM et al. | Common sources and composition of phytosterols and their estimated intake by the population in the city of São Paulo, Brazil. | 2013 | Nutrition | pmid:23422542 |
| Barbosa SP et al. | Effects of ezetimibe on markers of synthesis and absorption of cholesterol in high-risk patients with elevated C-reactive protein. | 2013 | Life Sci. | pmid:23507424 |
| Mo S et al. | Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry. | 2013 | Lipids | pmid:23884629 |