22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Hernández-Mijares A et al. | Low intestinal cholesterol absorption is associated with a reduced efficacy of phytosterol esters as hypolipemic agents in patients with metabolic syndrome. | 2011 | Clin Nutr | pmid:21489663 |
| Miettinen TA et al. | Non-cholesterol sterols in serum and endarterectomized carotid arteries after a short-term plant stanol and sterol ester challenge. | 2011 | Nutr Metab Cardiovasc Dis | pmid:20096545 |
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| Brindisi MC et al. | Liver fat content is associated with an increase in cholesterol synthesis independent of statin therapy use in patients with type 2 diabetes. | 2012 | Atherosclerosis | pmid:22959662 |
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| Vanmierlo T et al. | Dietary intake of plant sterols stably increases plant sterol levels in the murine brain. | 2012 | J. Lipid Res. | pmid:22279184 |
| Okada K et al. | Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease. | 2012 | Atherosclerosis | pmid:22892323 |
| Genser B et al. | Plant sterols and cardiovascular disease: a systematic review and meta-analysis. | 2012 | Eur. Heart J. | pmid:22334625 |
| Szakiel A et al. | Triterpenoid content of berries and leaves of bilberry Vaccinium myrtillus from Finland and Poland. | 2012 | J. Agric. Food Chem. | pmid:23157739 |
| Montserrat-de la Paz S et al. | The sterols isolated from Evening Primrose oil modulate the release of proinflammatory mediators. | 2012 | Phytomedicine | pmid:22819447 |
| Kurvinen A et al. | Parenteral plant sterols and intestinal failure-associated liver disease in neonates. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22197940 |
| Lupattelli G et al. | Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patients. | 2012 | Eur. J. Clin. Invest. | pmid:21793822 |
| Lupattelli G et al. | Non-cholesterol sterols in different forms of primary hyperlipemias. | 2012 | Nutr Metab Cardiovasc Dis | pmid:20708389 |
| Ito N et al. | An ultra performance liquid chromatographic method for determining phytosterol uptake by Caco-2 cells. | 2012 | Anal. Biochem. | pmid:22119071 |
| Jones ML et al. | Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. | 2012 | Eur J Clin Nutr | pmid:22990854 |
| Lupattelli G et al. | Cholesterol metabolism differs after statin therapy according to the type of hyperlipemia. | 2012 | Life Sci. | pmid:22554491 |