22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Whitaker BD and Nelson DL | Sterol synergism in Paramecium tetraurelia. | 1988 | J. Gen. Microbiol. | pmid:3221193 |
| Vuoristo M et al. | Serum plant sterols and lathosterol related to cholesterol absorption in coeliac disease. | 1988 | Clin. Chim. Acta | pmid:3383445 |
| Milhaud J et al. | Interaction of the polyene antibiotic filipin with model and natural membranes containing plant sterols. | 1988 | Biochim. Biophys. Acta | pmid:3401484 |
| Koivisto PV and Miettinen TA | Effect of ileal exclusion on plant sterol metabolism in familial hypercholesterolemia. | 1987 | Digestion | pmid:3443223 |
| Bhattacharyya AK and Eggen DA | Effect of dietary cholesterol level on plasma campesterol concentration in rhesus monkeys. | 1987 | Ann. Nutr. Metab. | pmid:3662438 |
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| Salen G et al. | Increased plasma cholestanol and 5 alpha-saturated plant sterol derivatives in subjects with sitosterolemia and xanthomatosis. | 1985 | J. Lipid Res. | pmid:3989379 |
| Jwanny EW and Rashad MM | Metabolism of methanol by yeast and SCP production. | 1985 | J. Basic Microbiol. | pmid:4093874 |
| Dayal B et al. | Identification of 5 alpha-stanols in patients with sitosterolemia and xanthomatosis: stereochemistry of the protonolysis of steroidal organoboranes. | 1982 | Steroids | pmid:6297129 |
| Bhattacharyya AK and Eggen DA | Effects of feeding cholesterol and mixed plant sterols on the fecal excretion of acidic steroids in rhesus monkeys. | 1984 | Atherosclerosis | pmid:6529445 |
| Nes WR et al. | Steric effects at C-20 and C-24 on the metabolism of sterols by Tetrahymena pyriformis. | 1981 | J. Lipid Res. | pmid:6793681 |
| Wang C et al. | A unique patient with coexisting cerebrotendinous xanthomatosis and beta-sitosterolemia. | 1981 | Am. J. Med. | pmid:7258222 |
| Yunker RL et al. | Simultaneous quantitation of biliary cholesterol, bile acids, and phospholipids (as fatty acids), by gas-liquid chromatography, with campesterol as internal standard. | 1981 | Clin. Chem. | pmid:7285335 |
| Miettinen TA et al. | Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population. | 1995 | N. Engl. J. Med. | pmid:7566021 |
| Lütjohann D et al. | Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment. | 1995 | J. Lipid Res. | pmid:7595097 |
| Locker PK et al. | Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group. | 1995 | Clin. Pharmacol. Ther. | pmid:7828385 |
| Davis RH et al. | Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation. | 1994 | J Am Podiatr Med Assoc | pmid:7853156 |
| Zeeck E et al. | Sex pheromones in marine polychaetes: steroids from ripe Nereis succinea. | 1994 | Steroids | pmid:8073448 |
| Heinemann T et al. | Comparison of intestinal absorption of cholesterol with different plant sterols in man. | 1993 | Eur. J. Clin. Invest. | pmid:8143759 |
| Ling WH and Jones PJ | Enhanced efficacy of sitostanol-containing versus sitostanol-free phytosterol mixtures in altering lipoprotein cholesterol levels and synthesis in rats. | 1995 | Atherosclerosis | pmid:8770325 |