22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Choi JM et al. | Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities. | 2007 | Phytother Res | pmid:17604370 |
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| Nagadome S et al. | Monolayers (Langmuir films) behavior of multi-component systems composed of a bile acid with different sterols and with their 1:1 mixtures. | 2007 | Colloids Surf B Biointerfaces | pmid:17482801 |
| Abramsson-Zetterberg L et al. | No evidence of genotoxic effect in vivo of the phytosterol oxidation products triols and epoxides. | 2007 | Toxicol. Lett. | pmid:17765410 |
| Pinedo S et al. | Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study. | 2007 | J. Lipid Res. | pmid:17074925 |
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| Takahashi K et al. | Metabolic conversion of 24-methyl-Delta25-cholesterol to 24-methylcholesterol in higher plants. | 2006 | Bioorg. Med. Chem. | pmid:16213729 |
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| Ikeda I et al. | Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPARalpha, promotes energy consumption and reduces visceral fat deposition in rats. | 2006 | Biochim. Biophys. Acta | pmid:16616424 |
| Gerloff T et al. | Influence of the SLCO1B1*1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16568260 |
| Hedman M et al. | Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy. | 2006 | J. Pediatr. | pmid:16492436 |
| Takahashi K et al. | Purification and ATPase activity of human ABCA1. | 2006 | J. Biol. Chem. | pmid:16500904 |
| de Jong A et al. | Plant sterol or stanol consumption does not affect erythrocyte osmotic fragility in patients on statin treatment. | 2006 | Eur J Clin Nutr | pmid:16482072 |
| Oswald S et al. | Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins. | 2006 | Clin. Pharmacol. Ther. | pmid:17112804 |
| Xu F et al. | Dual roles for cholesterol in mammalian cells. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16199524 |
| Nikkilä K et al. | Sterol parameters as markers of liver function in primary biliary cirrhosis before and after liver transplantation. | 2005 | Transpl. Int. | pmid:15691276 |
| Yu L et al. | Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8. | 2005 | J. Lipid Res. | pmid:15930515 |
| Miettinen TA et al. | Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endarterectomy. | 2005 | J. Am. Coll. Cardiol. | pmid:15936608 |
| Hong Z et al. | The Rice brassinosteroid-deficient dwarf2 mutant, defective in the rice homolog of Arabidopsis DIMINUTO/DWARF1, is rescued by the endogenously accumulated alternative bioactive brassinosteroid, dolichosterone. | 2005 | Plant Cell | pmid:15994910 |