22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Gylling H and Miettinen TA | Cholesterol absorption, synthesis, and LDL metabolism in NIDDM. | 1997 | Diabetes Care | pmid:9028702 |
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| Gylling H et al. | Oral guar gum treatment of intrahepatic cholestasis and pruritus in pregnant women: effects on serum cholestanol and other non-cholesterol sterols. | 1998 | Eur. J. Clin. Invest. | pmid:9650008 |
| Howell TJ et al. | Phytosterols partially explain differences in cholesterol metabolism caused by corn or olive oil feeding. | 1998 | J. Lipid Res. | pmid:9555952 |
| Klahre U et al. | The Arabidopsis DIMINUTO/DWARF1 gene encodes a protein involved in steroid synthesis. | 1998 | Plant Cell | pmid:9761794 |
| Schaller H et al. | Overexpression of an Arabidopsis cDNA encoding a sterol-C24(1)-methyltransferase in tobacco modifies the ratio of 24-methyl cholesterol to sitosterol and is associated with growth reduction. | 1998 | Plant Physiol. | pmid:9765531 |
| Ntanios FY and Jones PJ | Effects of variable dietary sitostanol concentrations on plasma lipid profile and phytosterol metabolism in hamsters. | 1998 | Biochim. Biophys. Acta | pmid:9487145 |
| Harsch M et al. | Effects of pravastatin on cholesterol metabolism of cholesterol-fed heterozygous WHHL rabbits. | 1998 | Br. J. Pharmacol. | pmid:9641543 |
| Del Puppo M et al. | Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway. | 1998 | J. Lipid Res. | pmid:9831637 |
| Srikumar TS et al. | Analysis of fecal bile acids and neutral steroids using gas-liquid chromatography. | 1998 | Ann. Nutr. Metab. | pmid:9745109 |