22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Feio CA et al. | Euterpe oleracea (açai) modifies sterol metabolism and attenuates experimentally-induced atherosclerosis. | 2012 | J. Atheroscler. Thromb. | pmid:22139433 |
| van den Kommer TN et al. | The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline. | 2012 | Neurobiol. Aging | pmid:21482441 |
| Vanmierlo T et al. | Dietary intake of plant sterols stably increases plant sterol levels in the murine brain. | 2012 | J. Lipid Res. | pmid:22279184 |
| Genser B et al. | Plant sterols and cardiovascular disease: a systematic review and meta-analysis. | 2012 | Eur. Heart J. | pmid:22334625 |
| Szakiel A et al. | Triterpenoid content of berries and leaves of bilberry Vaccinium myrtillus from Finland and Poland. | 2012 | J. Agric. Food Chem. | pmid:23157739 |
| Lupattelli G et al. | Non-cholesterol sterols in different forms of primary hyperlipemias. | 2012 | Nutr Metab Cardiovasc Dis | pmid:20708389 |
| Jones ML et al. | Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. | 2012 | Eur J Clin Nutr | pmid:22990854 |
| Wewer V et al. | Quantification of sterol lipids in plants by quadrupole time-of-flight mass spectrometry. | 2011 | J. Lipid Res. | pmid:21382968 |
| Lupattelli G et al. | Patterns of cholesterol metabolism: pathophysiological and therapeutic implications for dyslipidemias and the metabolic syndrome. | 2011 | Nutr Metab Cardiovasc Dis | pmid:21855307 |
| Labonté MÈ et al. | Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men. | 2011 | Mol Nutr Food Res | pmid:21656668 |
| Kurano M et al. | Plant sterols increased IL-6 and TNF-α secretion from macrophages, but to a lesser extent than cholesterol. | 2011 | J. Atheroscler. Thromb. | pmid:21266789 |
| Schröder M and Vetter W | High-speed counter-current chromatographic separation of phytosterols. | 2011 | Anal Bioanal Chem | pmid:21499948 |
| Vanmierlo T et al. | Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. | 2011 | Plant Foods Hum Nutr | pmid:21431910 |
| Husche C et al. | Validation of an isotope dilution gas chromatography-mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum. | 2011 | Chem. Phys. Lipids | pmid:21620808 |
| Kurvinen A et al. | Effects of long-term parenteral nutrition on serum lipids, plant sterols, cholesterol metabolism, and liver histology in pediatric intestinal failure. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21543999 |
| Valitova JN et al. | Effects of sterol-binding agent nystatin on wheat roots: the changes in membrane permeability, sterols and glycoceramides. | 2011 | Phytochemistry | pmid:21726881 |
| Shafaati M et al. | Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation. | 2011 | J. Lipid Res. | pmid:21335619 |
| Sabeva NS et al. | Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. | 2011 | J. Nutr. Biochem. | pmid:21111593 |
| de Araújo MF et al. | Simiranes A and B: erythroxylanes diterpenes and other compounds from Simira eliezeriana (Rubiaceae). | 2011 | Nat. Prod. Res. | pmid:21936665 |
| Niesor EJ et al. | Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects. | 2011 | Atherosclerosis | pmid:21982411 |