22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| van Dusseldorp M et al. | Cholesterol-raising factor from boiled coffee does not pass a paper filter. | 1991 May-Jun | Arterioscler. Thromb. | pmid:2029499 |
| Miettinen TA et al. | Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: relation to basal serum cholestanol. | 2000 | Arterioscler. Thromb. Vasc. Biol. | pmid:10807752 |
| van Himbergen TM et al. | Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19834104 |
| Devaraj S et al. | Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:14764424 |
| Ling WH and Jones PJ | Enhanced efficacy of sitostanol-containing versus sitostanol-free phytosterol mixtures in altering lipoprotein cholesterol levels and synthesis in rats. | 1995 | Atherosclerosis | pmid:8770325 |
| Ntanios FY et al. | Effects of various amounts of dietary plant sterol esters on plasma and hepatic sterol concentration and aortic foam cell formation of cholesterol-fed hamsters. | 2003 | Atherosclerosis | pmid:12860249 |
| Niesor EJ et al. | Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects. | 2011 | Atherosclerosis | pmid:21982411 |
| Miettinen TA et al. | Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study. | 2008 | Atherosclerosis | pmid:18178213 |
| Noto D et al. | Plasma non-cholesterol sterols in primary hypobetalipoproteinemia. | 2011 | Atherosclerosis | pmid:21492858 |