22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schuler I et al. | Soybean phosphatidylcholine vesicles containing plant sterols: a fluorescence anisotropy study. | 1990 | Biochim. Biophys. Acta | pmid:2207122 |
| Boberg KM et al. | Formation of C21 bile acids from plant sterols in the rat. | 1990 | J. Biol. Chem. | pmid:2335512 |
| Kempen HJ et al. | Lathosterol level in plasma is elevated in type III hyperlipoproteinemia, but not in non-type III subjects with apolipoprotein E2/2 phenotype, nor in type IIa or IIb hyperlipoproteinemia. | 1991 | Metab. Clin. Exp. | pmid:2000034 |
| Bhadra S and Subbiah MT | Incorporation of liposomal phytosterols into human cells in culture: a potential in vitro model for investigating pathological effects of phytosterolemia. | 1991 | Biochem. Med. Metab. Biol. | pmid:1931153 |
| Kuriyama M et al. | High levels of plant sterols and cholesterol precursors in cerebrotendinous xanthomatosis. | 1991 | J. Lipid Res. | pmid:2066659 |
| Nikkilä K et al. | High cholestanol and low campesterol-to-sitosterol ratio in serum of patients with primary biliary cirrhosis before liver transplantation. | 1991 | Hepatology | pmid:2010161 |
| van Dusseldorp M et al. | Cholesterol-raising factor from boiled coffee does not pass a paper filter. | 1991 May-Jun | Arterioscler. Thromb. | pmid:2029499 |
| Sutherland WH et al. | Plasma non-cholesterol sterols in patients with non-insulin dependent diabetes mellitus. | 1992 | Horm. Metab. Res. | pmid:1601392 |
| Vanhanen HT and Miettinen TA | Effects of unsaturated and saturated dietary plant sterols on their serum contents. | 1992 | Clin. Chim. Acta | pmid:1521345 |
| Nikkilä K et al. | Liver transplantation modifies serum cholestanol, cholesterol precursor and plant sterol levels. | 1992 | Clin. Chim. Acta | pmid:1499139 |