22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Okada K et al. | Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease. | 2012 | Atherosclerosis | pmid:22892323 |
| Montserrat-de la Paz S et al. | The sterols isolated from Evening Primrose oil modulate the release of proinflammatory mediators. | 2012 | Phytomedicine | pmid:22819447 |
| Kurvinen A et al. | Parenteral plant sterols and intestinal failure-associated liver disease in neonates. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22197940 |
| Lupattelli G et al. | Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patients. | 2012 | Eur. J. Clin. Invest. | pmid:21793822 |
| Lupattelli G et al. | Non-cholesterol sterols in different forms of primary hyperlipemias. | 2012 | Nutr Metab Cardiovasc Dis | pmid:20708389 |
| Ito N et al. | An ultra performance liquid chromatographic method for determining phytosterol uptake by Caco-2 cells. | 2012 | Anal. Biochem. | pmid:22119071 |
| Lupattelli G et al. | Cholesterol metabolism differs after statin therapy according to the type of hyperlipemia. | 2012 | Life Sci. | pmid:22554491 |
| Nes WD | Biosynthesis of cholesterol and other sterols. | 2011 | Chem. Rev. | pmid:21902244 |
| Gälman C et al. | Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19. | 2011 | J. Intern. Med. | pmid:22003820 |
| Miettinen TA et al. | Non-cholesterol sterols in serum and endarterectomized carotid arteries after a short-term plant stanol and sterol ester challenge. | 2011 | Nutr Metab Cardiovasc Dis | pmid:20096545 |