Ursocholic acid

Ursocholic acid is a lipid of Sterol Lipids (ST) class. The involved functions are known as Regulation, Biliary Fistula, Biochemical Pathway and Metabolic Inhibition. Ursocholic acid often locates in Hepatic. The associated genes with Ursocholic acid are NR5A2 gene, fetoprotein transcription factor and SLC10A2 gene. The related lipids are ursocholic acid and Butanols.

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Introduction

To understand associated biological information of Ursocholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ursocholic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ursocholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ursocholic acid?

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What functions are associated with Ursocholic acid?


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What lipids are associated with Ursocholic acid?

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What genes are associated with Ursocholic acid?

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What common seen animal models are associated with Ursocholic acid?

There are no associated biomedical information in the current reference collection.

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All references with Ursocholic acid

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Authors Title Published Journal PubMed Link
Poša M Heuman indices of hydrophobicity of bile acids and their comparison with a newly developed and conventional molecular descriptors. 2014 Biochimie pmid:24076126
Balmer ML et al. Effects of ursodeoxycholic acid in combination with vitamin E on adipokines and apoptosis in patients with nonalcoholic steatohepatitis. 2009 Liver Int. pmid:19422479
Cuesta de Juan S et al. Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis. 2007 J. Lipid Res. pmid:17332599
Chon CY and Park JY [Primary biliary cirrhosis]. 2006 Korean J Hepatol pmid:16998288
Li H et al. FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15591588
Harmand PO et al. Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells. 2005 Int. J. Cancer pmid:15523687
Batta AK et al. Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis. 2004 Metab. Clin. Exp. pmid:15131757
Xu G et al. Regulation of the farnesoid X receptor (FXR) by bile acid flux in rabbits. 2002 J. Biol. Chem. pmid:12401785
Nakashima T et al. Differences in the efficacy of ursodeoxycholic acid and bile acid metabolism between viral liver diseases and primary biliary cirrhosis. 2001 J. Gastroenterol. Hepatol. pmid:11350551
Nakashima T et al. A paucity of unusual trihydroxy bile acids in the urine of patients with severe liver diseases. 1999 Hepatology pmid:10216137