Ursocholic acid

Ursocholic acid is a lipid of Sterol Lipids (ST) class. The involved functions are known as Regulation, Biliary Fistula, Biochemical Pathway and Metabolic Inhibition. Ursocholic acid often locates in Hepatic. The associated genes with Ursocholic acid are NR5A2 gene, fetoprotein transcription factor and SLC10A2 gene. The related lipids are ursocholic acid and Butanols.

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Introduction

To understand associated biological information of Ursocholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ursocholic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ursocholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ursocholic acid?

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What functions are associated with Ursocholic acid?


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What lipids are associated with Ursocholic acid?

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What genes are associated with Ursocholic acid?

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What common seen animal models are associated with Ursocholic acid?

There are no associated biomedical information in the current reference collection.

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All references with Ursocholic acid

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Authors Title Published Journal PubMed Link
Aldini R et al. Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification. 1996 Steroids pmid:8910972
Dayal B et al. Microwave-induced organic reactions of bile acids: esterification, deformylation and deacetylation using mild reagents. 1995 Steroids pmid:7676478
Tint GS et al. Metabolism of ursocholic acid in humans: conversion of ursocholic acid to deoxycholic acid. 1992 Hepatology pmid:1551642
Xu G et al. Glycocholic acid and glycodeoxycholic acid but not glycoursocholic acid inhibit bile acid synthesis in the rabbit. 1992 Gastroenterology pmid:1568582
Dayal B and Salen G Stereospecific synthesis and two-dimensional 1H-NMR investigation of isoursocholic acid. 1991 J. Lipid Res. pmid:1770320
Roda A et al. Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC. 1990 J. Lipid Res. pmid:2280184
Lanzini A et al. Effect of chronic ursocholic acid administration on bile lipid composition and bile acid pool size in gallstone patients. 1990 Scand. J. Gastroenterol. pmid:2396085
Aldini R et al. Uptake of bile acids by perfused rat liver: evidence of a structure-activity relationship. 1989 Hepatology pmid:2807164
Howard PJ et al. Ursocholic acid: bile acid and bile lipid dose response and clinical studies in patients with gall stones. 1989 Gut pmid:2920932
Roda A et al. 23-Methyl-3 alpha,7 beta-dihydroxy-5 beta-cholan-24-oic acid: dose-response study of biliary secretion in rat. 1988 Nov-Dec Hepatology pmid:3192170