Trihydroxycoprostane

Trihydroxycoprostane is a lipid of Sterol Lipids (ST) class. The involved functions are known as Uptake, Enterohepatic Circulation, Metabolic Inhibition and Ionization. Trihydroxycoprostane often locates in Hepatic, Entire gastrointestinal tract and Abdominal Cavity. The related lipids are 3,7,12-trihydroxycoprostane, (3beta,5beta,7alpha,12alpha)-isomer, Cholestanes and scymnol.

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Introduction

To understand associated biological information of Trihydroxycoprostane, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Trihydroxycoprostane

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Trihydroxycoprostane?

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What functions are associated with Trihydroxycoprostane?


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What lipids are associated with Trihydroxycoprostane?

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What genes are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Trihydroxycoprostane?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Trihydroxycoprostane

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Authors Title Published Journal PubMed Link
Une M et al. Comparative studies on omega-hydroxylation of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol in the mitochondrial and microsomal fraction of the liver from several vertebrates. 1997 Steroids pmid:9185292
Fricker G et al. Enterohepatic circulation of scymnol sulfate in an elasmobranch, the little skate (Raja erinacea). 1997 Am. J. Physiol. pmid:9374698
Betsholtz IH and Wikvall K Cytochrome P450 CYP27-catalyzed oxidation of C27-steroid into C27-acid. 1995 J. Steroid Biochem. Mol. Biol. pmid:7577714
Ikegawa S et al. Stereoisomeric inversion of (25R)- and (25S)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acids in rat liver peroxisome. 1995 Biol. Pharm. Bull. pmid:7581245
Dahlbäck H and Holmberg I Oxidation of 5 beta-cholestane-3 alpha,7 alpha, 12 alpha-triol into 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid by cytochrome P-450(26) from rabbit liver mitochondria. 1990 Biochem. Biophys. Res. Commun. pmid:2322231
Saarem K and Pedersen JI Effect of age, gonadectomy and hypophysectomy on mitochondrial hydroxylation of vitamin D3 (cholecalciferol) and of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol in female and male rat liver. 1988 Biochem. J. pmid:2840896
Saarem K and Pedersen JI Sex differences in the hydroxylation of cholecalciferol and of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol in rat liver. 1987 Biochem. J. pmid:2825658
Skrede S et al. Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis. 1986 J. Clin. Invest. pmid:3745434
Lidström-Olsson B and Wikvall K The role of sterol carrier protein2 and other hepatic lipid-binding proteins in bile-acid biosynthesis. 1986 Biochem. J. pmid:3800967
Shimazu K et al. Bile alcohol profiles in bile, urine, and feces of a patient with cerebrotendinous xanthomatosis. 1986 J. Biochem. pmid:3700361